60769-23-5Relevant academic research and scientific papers
Facile and efficient synthesis of hydroxyalkyl esters from cyclic acetals through aerobic photo-oxidation using anthraquinone-2-carboxylic acid
Yamaguchi, Tomoaki,Kudo, Yasuhisa,Hirashima, Shin-ichi,Yamaguchi, Eiji,Tada, Norihiro,Miura, Tsuyoshi,Itoh, Akichika
, p. 1973 - 1975 (2015/03/18)
Abstract A convenient metal-free oxidation protocol of various cyclic acetals with molecular oxygen and anthraquinone-2-carboxylic acid under visible light irradiation by a fluorescent lamp afforded their corresponding hydroxyalkyl esters.
Facile oxidative hydrolysis of acetals to esters using hypervalent iodine(III)/LiBr combination in water
Panchan, Waraporn,Chiampanichayakul, Supanimit,Snyder, Deanna L.,Yodbuntung, Siriporn,Pohmakotr, Manat,Reutrakul, Vichai,Jaipetch, Thaworn,Kuhakarn, Chutima
experimental part, p. 2732 - 2735 (2010/05/17)
The combination of (diacetoxy)iodobenzene (PhI(OAc)2, DIB) and lithium bromide (LiBr) efficiently oxidized cyclic and acyclic acetals to the corresponding hydroxyalkyl carboxylic esters and simple esters in good to excellent yields. The merits of this reaction are that it employs commercially available and non-explosive hypervalent iodine(III) reagent, water as the solvent, a short reaction time, and mild reaction conditions.
2-Iodoxybenzoic acid/tetraethylammonium bromide/water: An efficient combination for oxidative cleavage of acetals
Kuhakarn, Chutima,Panchan, Waraporn,Chiampanichayakul, Supanimit,Samakkanad, Natthapol,Pohmakotr, Manat,Reutrakul, Vichai,Jaipetch, Thaworn
experimental part, p. 929 - 934 (2009/10/14)
A simple and efficient procedure has been developed for the oxidation of cyclic and acyclic acetals to the corresponding hydroxyalkyl carboxylic esters and simple esters, respectively. 2-Iodoxybenzoic acid (IBX) in the presence of tetraethylammonium bromide was employed for the reaction in aqueous media. The salient features of the protocol include short reaction time, environmentally benign reagents and solvent, and moderate to high yields. Georg Thieme Verlag Stuttgart.
Fluorescent inhibitors for IspF, an enzyme in the non-mevalonate pathway for isoprenoid biosynthesis and a potential target for antimalarial therapy
Crane, Christine M.,Kaiser, Johannes,Ramsden, Nicola L.,Lauw, Susan,Rohdich, Felix,Eisenreich, Wolfgang,Hunter, William N.,Bacher, Adelbert,Diederich, Francois
, p. 1069 - 1074 (2007/10/03)
Designed inhibitors (like 1) of IspF, a key enzyme in the non-mevalonate pathway for terpene biosynthesis and a potential antimalarial target, were synthesized and evaluated. Since fluorescent probes were introduced in these ligands, their affinity toward
