608-39-9Relevant academic research and scientific papers
Stereoselective homogeneous hydrogenation. The basis of preferential anti-isomer formation in acyclic systems
Brown, John M.,Cutting, Ian,James, Alun P.
, p. 211 - 217 (2007/10/02)
Directed homogeneous hydrogenation of olefins derived from methyl acrylate proceeds with high selectivity.The reactant must possess a polar substituent at a chiral centre situated in the α'-position; this may be -OH, CO2R or NHCOR.The catalyst should be a cationic chelating rhodium biphosphine complex.In all cases high anti-stereoselectivity is observed in the reduced product, and this can be rationalised by a simple and general model.With an optically active catalyst, efficient kinetic resolution occurs, providing a means of access to optically active acrylates.Experimental details of typical hydrogenation reactions are provided.
HIGHLY DIASTEREOSELECTIVE TANDEM ALKYLATION OF ACYCLIC α,β-UNSATURATED ESTERS BASED ON THE NOVEL USE OF DITHIOACETAL UNIT
Kawasaki, Hisashi,Tomioka, Kiyoshi,Koga, Kenji
, p. 3031 - 3034 (2007/10/02)
Highly diastereoselective tandem alkylation process of acyclic α,β-unsaturated esters was developed based on the novel use of dithioacetal as a stereocontrolling unit.
OXIDATIVE COUPLING REACTIONS UNDER PTC CONDITIONS
Gogte, V.N.,Natu, A.A.,Pandit, V.S.
, p. 4131 - 4134 (2007/10/02)
Succinic acid derivatives have been prepared from cyanohalides under PTC conditions in good yields.
DIMETALATED TERTIARY SUCCINAMIDES. ALKYLATION AND ANNELATION REACTIONS
Mahalanabis, K.K.,Mumtaz, M.,Snieckus, V.
, p. 3971 - 3974 (2007/10/02)
The reactions of dimetalated succinamides 1 with a variety of electrophiles give 2,3-disubstituted adducts (2) with high diasterioselectivity and annelated products (6-9).
