60884-08-4

Usage

Preparation

Preparation by reaction of pivaloyl chloride with 1,3-di-methoxybenzene in the presence of stannic chloride/hydrochloric acid gas in nitromethane at r.t. for 6 days (quantitative yield).

Upstream product

• 3282-30-2 pivaloyl chloride 
• 151-10-0 1,3-Dimethoxybenzene 
• 111122-89-5 2-tert-Butyl-2-(2,4-dimethoxy-phenyl)-benzo[1,3]oxathiole 
• 111123-03-6 2-(2-tert-Butyl-benzo[1,3]oxathiol-2-yl)-1,3-dimethyl-1H-indole 
• 39828-35-8 2,4-dimethoxybenzoyl chloride 
• 594-19-4 tert.-butyl lithium 
• 111122-90-8 2-(2,4-Dimethoxy-phenyl)-2-phenyl-benzo[1,3]oxathiole 
• 59045-53-3 2-tert-butyl-1,3-benzoxathiolium tetrefluoroborate 
• 60884-07-3 1-(2,4-dihydroxyphenyl)-2,2-dimethylpropan-1-one 
• 77-78-1 dimethyl sulfate 

Relevant academic research and scientific papers

Chiral phosphoric acid catalyzed asymmetric transfer hydrogenation of bulky aryl ketones with ammonia borane

An asymmetric transfer hydrogenation of bulky aryl ketones with ammonia borane was successfully realized with chiral phosphoric acid (CPA) as catalyst and water as additive. A variety of optically active secondary alcohols were obtained in good to high yi

Catalysis of the acylation of aromatic derivatives by metallic tosylates

A series of metallic tosylates were prepared by ultrasonic metal activation and were further used as efficient catalysts for the acylation of aromatic derivatives.

Friedel-Crafts acylation using bismuth triflate in [BMI][PF6]

Bismuth trifluoromethanesulfonate was found to be a good catalyst for the Friedel-Crafts acylation. Bismuth triflate immobilized in an ionic liquid was the most efficient catalytic system. Bismuth triflate in [BMI][PF6] catalyzes this reaction under microwave irradiation allowing the rapid synthesis of aryl ketones in excellent yields. The catalyst system was easily recovered and reused several times.

2-Substituted 1,3-Benzoxathiolium Tetrafluoroborates as Useful Acylating Agents of Electron-Rich Aromatic and Heteroaromatic Compounds

2-Substituted 1,3-benzoxathiolium tetrafluoroborates were used for the two-step acylation of electron-rich aromatic and heteroaromatic compounds: 1,3-dimethoxybenzene, 1,3,5-trimethoxybenzene, pyrrole and indoles.In most of the cases intermediate 2,2-disubstituted 1,3-benzoxathioles were obtained in good to high yields (55-100percent) and subsequent hydrolysis of these with mercury(II) oxide and aqueous tetrafluoroboric acid (35percent) in tetrahydrofuran afforded the corresponding ketones in almost quantitative yields.