60912-61-0Relevant articles and documents
Conformational and Chiral Properties of Cyclic-tri(N-methyl-meta-benzamide) Bearing Amidino Groups
Nishiyama, Shizuka,Urushibara, Ko,Masu, Hyuma,Azumaya, Isao,Kagechika, Hiroyuki,Tanatani, Aya
, p. 487 - 491 (2015)
Cyclic triamides 4 bearing amidino groups at the meta position of the phenyl rings were synthesized, and their conformational properties in the crystal and in solution were examined. Compound 4a exists as a capsule-type dimer of the enantiomers with a bowl-shaped syn conformation in the crystal state. Compound 4 exists mainly in the syn form in solution, and chiral induction was observed upon addition of a chiral acid to a solution of 4a. Chirality 27:487-491, 2015.
Cyclic-tri(N-methyl-meta-benzamide)s: Substituent effects on the bowl-shaped conformation in the crystal and solution states
Kakuta, Hiroki,Azumaya, Isao,Masu, Hyuma,Matsumura, Mio,Yamaguchi, Kentaro,Kagechika, Hiroyuki,Tanatani, Aya
experimental part, p. 8254 - 8260 (2010/11/02)
Cyclic trimers of 3-(N-alkylamino)benzoic acid (calix[3]amides) with various substituents at the meta position of the phenyl rings were synthesized and the effects of the substituents on the crystal structures and energy profiles in solution were examined. The calixamides existed in a syn conformation in the crystal state, and this was also the major conformation in solution, especially in polar solvents. The energy barrier between syn and anti conformers in the solution was not significantly affected by substituents (12.7-14.0 kcal/mol). The effect of the substituent on the temperature dependence of the syn/anti ratio are discussed.
