609799-32-8Relevant academic research and scientific papers
Chiral diamides as efficient catalytic precursors for the borane-mediated asymmetric reduction of prochiral ketones
Basavaiah, Deevi,Venkateswara Rao, Kalapala,Sekhara Reddy, Bhavanam
, p. 968 - 974 (2008/02/03)
Chiral diamides [(2S)-5-oxo-2-(arylamino)carbonylpyrrolidines] derived from the abundantly available (S)-glutamic/(S)-pyroglutamic acids were successfully utilized as effective chiral catalytic precursors in the borane-mediated asymmetric reduction of prochiral ketones in refluxing toluene, to provide the corresponding secondary alcohols with up to 91% enantiomeric purities.
Synthesis and application to asymmetric allylic amination of substituted monodonor diazaphospholidine ligands
Edwards, Christopher W.,Shipton, Mark R.,Alcock, Nathaniel W.,Clase, Howard,Wills, Martin
, p. 6473 - 6480 (2007/10/03)
The synthesis of a series of substituted monodonor diazaphospholidine ligands is described. A regioselective lithiation process is a key step in one of these syntheses. The compounds are designed to be incorporated into soluble polymer and other solid pha
