610-60-6

Basic information

• Product Name: methyl benzoylsalicylate
• Synonyms: methyl benzoylsalicylate;2-(Benzoyloxy)benzoic acid methyl ester;2-Benzoyloxybenzoic acid methyl ester;Benzoic acid 2-(methoxycarbonyl)phenyl ester;Benzosalin;VFRPYBIGSSNAJS-UHFFFAOYSA-N
• CAS NO: 610-60-6
• Molecular Formula: C₁₅H₁₂O₄
• Molecular Weight: 256.2534
• Mol File: 610-60-6.mol
• Article Data: 10

Chemical Properties

• Melting Point: 85°
• Boiling Point: bp 385°
• Flash Point: 193.8°C
• Appearance: /
• Density: 1.215g/cm³
• Vapor Pressure: 3.77E-06mmHg at 25°C
• Refractive Index: 1.575
• CAS DataBase Reference: methyl benzoylsalicylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl benzoylsalicylate(610-60-6)
• EPA Substance Registry System: methyl benzoylsalicylate(610-60-6)

Safety Data

• Hazardous Substances Data: 610-60-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H12O4/c1-18-15(17)12-9-5-6-10-13(12)19-14(16)11-7-3-2-4-8-11/h2-10H,1H3

Upstream product

• 98-88-4 benzoyl chloride 
• 119-36-8 methyl salicylate 
• 93-97-0 benzoic acid anhydride 
• 129103-70-4 2-iodophenyl benzoate 
• 79-22-1 methyl chloroformate 
• 100-42-5 styrene 
• 4578-66-9 o-benzoyloxybenzoic acid 
• 74-88-4 methyl iodide 
• 65-85-0 benzoic acid 
• 4004-52-8 tris(methyl salicylate)phoshate ester 
• 100-51-6 benzyl alcohol 
• 186581-53-3 diazomethane 
• 577-85-5 3-hydroxyflavone 
• 82091-12-1 dimethyl 2,2’-(carbonylbis(oxy))dibenzoate 

Downstream Products

• 64780-03-6 5-benzoyl-2-hydroxy-benzoic acid methyl ester 
• 65-85-0 benzoic acid 
• 119-36-8 methyl salicylate 

Relevant articles and documents

Copper-catalyzed chemoselective oxidative o-aroylation of 2-acetylphenols, alkyl salicylates and 1,3-dicarbonyl compounds using styrene derivatives

A novel copper-catalyzed chemoselective oxidative O-aroylation of 2-acetylphenols, alkyl salicylates and 1,3-dicarbonyl compounds with a wide range of styrene derivatives are described. This approach provides an efficient chemoselective preparation of phenol, alkyl salicylate and enol esters in good to excellent yields. This method represents an alternative protocol for the classical esterification reactions.

Chemoselective generation of acyl phosphates, acylium ion equivalents, from carboxylic acids and an organophosphate ester in the presence of a Br?nsted acid

We describe the chemoselective conversion of carboxylic acids to functional aromatic ketones promoted by a tailored organophosphate ester in the presence of a Br?nsted acid. The protonated phosphate ester reacts with the carboxylic acid to form acyl phosphate, which reacts with benzenes to give aromatic ketones, probably through the acylium ion or its equivalent. The reaction time is short even at room temperature, and the reaction is compatible with various other functional groups, including amines, olefins, esters, amides and nitriles.

Cu(II)-catalyzed oxidative esterification of 2-carbonyl substituted phenols from the alcohol oxidation level

A copper-catalyzed oxidative esterification of 2-carbonyl substituted phenols from the alcohol oxidation level is described. This protocol represents direct access to a range of 2-carbonylated aryl benzoate derivatives, which are important building blocks in the synthesis of natural and pharmacological compounds.