6110-02-7

Upstream product

• 590-90-9 1-Hydroxy-3-butanone 
• 106-45-6 para-thiocresol 
• 78-94-4 methyl vinyl ketone 

Downstream Products

• 134209-09-9 3-hydroxy-3,4-dimethylpentyl p-methylphenyl sulfide 
• 91427-19-9 3-chloro-4-p-tolylsulfanyl-butan-2-one 
• 146388-10-5 (R)-4-(p-Tolylthio)butan-2-ol 
• 126665-18-7 3-hydroxybutyl p-tolyl sulfoxide 
• 126665-36-9 (E)-3,4-dimethyl-2-pentenyl p-tolyl sulfone 
• 126665-30-3 3-hydroxy-3,4-dimethylpentyl p-tolyl sulfone 
• 126665-32-5 3-isopropyl-3-butenyl p-tolyl sulfone 
• 150666-75-4 3-hydroxy-3,4-dimethylpentyl p-tolyl sulfoxide 
• 105363-56-2 (3-hydroxy)butyl p-tolyl sulfone 
• 34726-98-2 (E)-4-(p-tolylthio)-3-buten-2-one 
• 34726-97-1 (Z)-4-(p-tolylthio)-3-buten-2-one 
• 126665-13-2 3-hydroxybutyl p-tolyl sulfide 

Relevant academic research and scientific papers

Photo-Biocatalytic Cascades for the Synthesis of Volatile Sulfur Compounds and Chemical Building Blocks

Biocatalysis is a branch of catalysis that exploits enzymes to perform highly stereoselective chemical transformations under mild and sustainable conditions. This Synpact highlights how biocatalysis can be used in the synthesis of chiral 1,3-mercaptoalkan

Photo-biocatalytic One-Pot Cascades for the Enantioselective Synthesis of 1,3-Mercaptoalkanol Volatile Sulfur Compounds

The synthesis of enantiomerically pure 1,3-mercaptoalkanol volatile sulfur compounds through a one-pot photo-biocatalytic cascade reaction is described. Two new KRED biocatalysts with opposite enantioselectivity were discovered and proved to be efficient

Anodic generation of a zirconium catalyst for Ferrier rearrangement and hetero Michael addition

An efficient catalyst for Ferrier rearrangement and hetero-Michael addition was successfully generated from a sacrificial zirconium anode into media containing reactants for these reactions. Thus, the catalyst generated, successfully promoted the allylic

Squaric acid as an impressive organocatalyst for Michael addition in water

A simple, green, and environmentally benign protocol for squaric acid (5 mg) catalyst conjugate addition of aromatic amines and thiols to unsaturated carbonyl compounds in water in good to excellent yields is developed. The advantages of low sensitivity toward moisture and oxygen, high tolerance of different functional groups, green reaction media and efficient recyclability make this organocatalyst suitable for both laboratory and industrial scale synthesis of β-substituted carbonyls under very mild conditions.

Green, efficient and practical Michael addition of arylamines to α,β-unsaturated ketones

The aza-Michael addition of aromatic amines to α,β-unsaturated ketones was carried out effectively at room temperature in good to excellent yields without any catalyst or solvent. It was significant that part of adducts could be collected in almost quanti

"On-water" conjugate additions of anilines

The conjugate addition of anilines onto unsaturated ketones, esters and N-acylpyrroles was investigated. Based on a recently proposed explanation for the phenomenon of on-water catalysis, operationally simple and mild reaction conditions for effecting these addition reactions have been developed. The success of these additions provides further support for the acid-catalysed nature of on-water chemistry.

An economical noncatalytic approach to the synthesis of congested diaryl ethers and aryl benzyl thioethers through C-C insertion

An efficient one-pot synthesis of diaryl ethers and aryl benzyl thioethers has been delineated through base-induced ring transformation of 6-aryl-4-methylthio-2H-pyran-2-one-3-carbonitriles, methyl 6-aryl-4-methylthio- 2H-pyran-2-one-3-carboxylates and 6-aryl-4-(piperidin-1-yl)-2H-pyran-2-one-3- carbonitriles by either 1-phenoxypropan-2-one, 1,3-diphenoxypropan-2-one or 4-arylthiobutan-2-one, under very mild reaction conditions, in excellent yield. Georg Thieme Verlag Stuttgart.

Triethylammonium acetate (TEAA): A recyclable inexpensive ionic liquid promotes the chemoselective aza- and thia-Michael reactions

A new, highly efficient, inexpensive, recyclable, mild, convenient, and green protocol for chemoselective aza/thia-Michael addition reactions of amines/thiols to α,β-unsaturated compounds using triethylammonium acetate (TEAA) ionic liquid was developed. The catalyst can be recycled ten times and obviate the need for toxic and expensive catalysts.

Fluoroboric acid adsorbed on silica-gel (HBF4-SiO2) as a new, highly efficient and reusable heterogeneous catalyst for thia-Michael addition to α,β-unsaturated carbonyl compounds

Fluoroboric acid adsorbed on silica-gel (HBF4-SiO2) has been found to be a new and highly efficient heterogeneous catalyst for thia-Michael addition to α,β-unsaturated carbonyl compounds under solvent-free conditions. In the case of

Amino acid catalyzed thio-Michael addition reactions

Using amino acid as a catalyst, an inexpensive, nontoxic, environmentally friendly, metal-free reaction procedure for C-S bond formation via thio-Michael addition reaction has been developed. The thio-Michael addition products were obtained in excellent yields under mild and neutral conditions. This metal-free catalytic protocol was found to be a good alternative to the existing metal catalyst methodology for the thio-Michael addition reaction.