611182-70-8Relevant articles and documents
Enantioselective syntheses of aeruginosin 298-A and its analogues using a catalytic asymmetric phase-transfer reaction and epoxidation
Ohshima, Takashi,Gnanadesikan, Vijay,Shibuguchi, Tomoyuki,Fukuta, Yuhei,Nemoto, Tetsuhiro,Shibasaki, Masakatsu
, p. 11206 - 11207 (2007/10/03)
We developed a versatile synthetic process for aeruginosin 298-A as well as several attractive analogues, in which all stereocenters were controlled by a catalytic asymmetric phase-transfer reaction and epoxidation. Furthermore, drastic counteranion effects in phase-transfer catalysis were observed for the first time, making it possible to three-dimensionally fine-tune the catalyst (ketal part, aromatic part, and counteranion). Copyright