119244-19-8Relevant academic research and scientific papers
Cyclopeptoids as phase-transfer catalysts for the enantioselective synthesis of α-amino acids
Schettini, Rosaria,Nardone, Brunello,De Riccardis, Francesco,Sala, Giorgio Della,Izzo, Irene
, p. 7793 - 7797 (2014)
The first application of cyclopeptoids in asymmetric phasetransfer catalysis was examined. A small library of nine alternating N-substituted-glycine and proline hexacyclopeptoids was tested in the enantioselective alkylation of N-(diphenyl-methylene)glyci
Chiral phosphine-free Pd-mediated asymmetric allylation of prochiral enolate with a chiral phase-transfer catalyst
Nakoji, Masayoshi,Kanayama, Takatoshi,Okino, Tomotaka,Takemoto, Yoshiji
, p. 3329 - 3331 (2001)
Equation presented A chiral phase-transfer catalyst has been applied to the asymmetric allylation of the tert-butyl glycinate-benzophenone Schiff base with various allylic acetates for the first time to give the allylated products in good yields and with comparable to higher enantioselectivity than for asymmetric alkylation at the same temperature (91-96% ee) without any chiral ligands for coordinating to the palladium.
A New Active Catalyst Species for Enantioselective Alkylation by Phase-Transfer Catalysis
O'Donnell, Martin J.,Wu, Shengde,Huffman, John C.
, p. 4507 - 4518 (1994)
This paper briefly reviews the use of Schiff base substrates in amino acid synthesis.Recent studies lead to the proposal of a new active catalyst species (12) for the asymmetric PTC alkylation of active methylene compounds (2).Mechanistic implications are
Highly efficient ortho-fluoro-dimeric cinchona-derived phase-transfer catalysts
Park, Hyeung-Geun,Jeong, Byeong-Seon,Yoo, Mi-Sook,Lee, Jeong-Hee,Park, Boon-Saeng,Kim, Myoung Goo,Jew, Sang-Sup
, p. 3497 - 3500 (2003)
A series of cinchona alkaloid-derived dimeric quaternary ammonium salts were prepared as chiral phase-transfer catalysts by the introduction of various functional groups on the phenyl ligand. Among them, the 2-F-substituted derivative 21 showed the highes
Heterogeneous simplified Maruoka phase-transfer catalyst tethered on poly(styrene-co-acrylamide) microsphere: Structure-activity relationship in enantioselective Α-alkylation
Feng, Dandan,Wan, Jingwei,Teng, Fei,Ma, Xuebing
, p. 127 - 133 (2017)
The covalent immobilization of valuable simplified Maruoka catalyst onto poly(styrene-co-acrylamide)microsphere at different locations was developed for the first time through the copolymerization of Maruoka catalyst-functionalized styrene with styrene an
The asymmetric alkylation reaction of glycine derivatives catalyzed by the novel chiral phase transfer catalysts
Wang, Ziyu,Huang, Daorui,Xu, Pei,Dong, Xiaoyang,Wang, Xiaolong,Dai, Zhenya
, p. 1067 - 1071 (2015)
Herein a new series of chiral phase transfer catalysts derived from the cinchona alkaloids were synthesized and applied in the asymmetric alkylation of glycine derivatives with high yields and moderate to excellent ee values (39.5-99.7%).
Dimeric cinchona ammonium salts with benzophenone linkers: Enantioselective phase transfer catalysts for the synthesis of α-Amino acids
Woo, Seunga,Kim, Yong-Gyun,Lim, Baegeun,Oh, Jiin,Lee, Yeonji,Gwon, Hyeri,Nahm, Keepyung
, p. 2157 - 2160 (2018)
Chiral phase transfer catalysts of dimeric cinchona ammonium salts linked with a benzophenone bridge showed high enantioselectivity in the α-Alkylation of a glycinate ester under mild industry-Applicable conditions: 0.5 mol% PTC and near equivalents of al
A new class of acetophenone-based cinchona alkaloids as phase-transfer catalysts: Application to the enantioselective synthesis of α-amino acids
Lv, Jian,Zhang, Liping,Liu, Lei,Wang, Yongmei
, p. 1354 - 1355 (2007)
A new class of acetophenone-based cinchona alkaloid-de-rived quaternary ammonium salts were prepared and evaluated as phase-transfer catalysts in the enantioselective alkylation of glycine imine ester. +R 3N-CH2COAr and el
Synthesis and application of dimeric Cinchona alkaloid phase-transfer catalysts: α,α′-bis[O(9)-allylcinchonidinium]-o, m, or p-xylene dibromide
Jew,Jeong,Yoo,Huh,Park
, p. 1244 - 1245 (2001)
A dimeric Cinchona alkaloid ammonium salt, α,α′-bis[O(9)-allylcinchonidinium]-m-xylene dibromide 4, has been developed as a new efficient phase-transfer catalyst; the catalytic enantioselective alkylation of N-(diphenylmethylene)glycine tert-butyl ester u
Combinatorial approach for the design of new, simplified chiral phase-transfer catalysts with high catalytic performance for practical asymmetric synthesis of α-alkyl-α-amino acids
Kitamura, Masanori,Arimura, Yuichiro,Shirakawa, Seiji,Maruoka, Keiji
, p. 2026 - 2030 (2008)
A very efficient, chiral phase-transfer catalyst (S)-2Db was prepared by taking advantage of the combinatorial approach from the known, easily available (S)-1,1′-binaphthyl-2,2′-dicarboxylic acid. This catalyst exhibited the high catalytic performance (0.
