139033-70-8

Basic information

• Product Name: L-Arg(δ,ω'-di-Cbz)-OMe
• Synonyms: L-Arg(δ,ω'-di-Cbz)-OMe
• CAS NO: 139033-70-8
• Molecular Weight: 456.499
• Mol File: 139033-70-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: L-Arg(δ,ω'-di-Cbz)-OMe(CAS DataBase Reference)
• NIST Chemistry Reference: L-Arg(δ,ω'-di-Cbz)-OMe(139033-70-8)
• EPA Substance Registry System: L-Arg(δ,ω'-di-Cbz)-OMe(139033-70-8)

Safety Data

• Hazardous Substances Data: 139033-70-8(Hazardous Substances Data)

Upstream product

• 162007-07-0 methyl (2S)-(tert-butoxycarbonylamino)-5-hydroxypentanoate 
• 10065-79-9 N₁,N₂-bis(benzyloxycarbonyl)guanidine 
• 24277-39-2 N-tert-butoxycarbonyl glutamic acid tert-butyl ester 
• 50299-15-5 methyl (S)-allylglycinate 
• 119244-19-8 tert-butyl (S)-2-[(diphenylmethylene)amino]pent-4-enoate 
• 89985-87-5 methyl (2S)-2-tert-butoxycarbonylamino-4-pentenoate 
• 95198-94-0 C₁₁H₂₀NO₄CN₃H₂(C₈H₇O₂)2 
• 611182-62-8 N-(diphenylmethylene)-L-glutamic acid 1-(1,1-dimethylethyl) 5-benzyl ester 

Downstream Products

• 139033-54-8 Z-Trpψ(CH2NH)Arg(Z2)-OMe 
• 611182-70-8 TIPSO-D-Hpla(TIPS)-D-Leu-L-Choi(TIPS)-L-Arg(δ,ω'-di-Cbz)-OMe 
• 611182-71-9 TIPSO-D-Hpla(TIPS)-D-Leu-L-Choi(TIPS)-L-Argol(δ,ω'-di-Cbz) 
• 611182-68-4 Boc-L-Choi(TIPS)-L-Arg(δ,ω'-di-Cbz)-OMe 
• 611182-69-5 C₄₁H₆₁N₅O₈Si 
• 611182-67-3 C₃₇H₄₉N₅O₁₀ 

Relevant articles and documents

Catalytic asymmetric phase-transfer reactions using tartrate-derived asymmetric two-center organocatalysts

A new highly versatile asymmetric two-center catalyst, tartrate-derived diammonium salt (TaDiAS), was designed and a catalyst library containing more than 70 new two-center catalysts was constructed. A variety of (S,S)- and (R,R)-TaDiAS were easily synthesized from diethyl L- and D-tartrate, respectively, using common and inexpensive reagents under operationally simple reaction conditions. TaDiAS was used in phase-transfer alkylations and Michael additions to afford various optically active α-amino acid equivalents in up to 93% yield. Moreover, dramatic counter anion effects were observed in phase-transfer catalysis (PTC) for the first time, making it possible to further improve reactivity and selectivity. These findings validate the usefulness of three-dimensional fine-tuning of the catalyst (acetal, Ar, and counter anion) for optimization. Recovery and reuse of the catalyst was also possible using simple procedures. The present asymmetric PTC was successfully applied to enantioselective syntheses of serine protease inhibitor aeruginosin 298-A and its analogues.