61122-85-8

Upstream product

• 856815-39-9 2-(2-imino-2H-[1]pyridyl)-1,3-diphenyl-propane-1,3-dione 
• 504-29-0 2-aminopyridine 
• 98-86-2 acetophenone 
• 100-52-7 benzaldehyde 
• 21170-60-5 1,3-diphenyl-3-pyridin-2-ylamino-propenone 
• 6935-27-9 N-benzylpyridin-2-amine 
• 536-74-3 phenylacetylene 
• 614-47-1 1,3-diphenyl-propen-3-one 
• 7338-94-5 1,3-diphenyl-2-propynone 
• 98-88-4 benzoyl chloride 
• 120422-18-6 (Z)-1,3-diphenyl-3-(pyridin-2-ylamino)prop-2-en-1-one 
• 120-46-7 1,3-diphenylpropanedione 
• 159639-03-9 1,3-diphenyl-3-(pyridin-2-yl)aminopropan-1-one 
• 94-41-7 benzalacetophenone 

Relevant academic research and scientific papers

Copper-catalyzed oxidative multicomponent reaction: Synthesis of imidazo fused heterocycles with molecular oxygen

An oxidative cascade that involves multicomponent reaction comprising a terminal alkyne, 2-amino N-heterocycle, benzyl or allylic bromide with molecular oxygen, delivering densely functionalized imidazo fused heterocycles, is described. This reaction features a cheap catalyst, a green oxidant, and readily available starting materials, which make the overall synthesis applicable in the quick access to relevant pharmaceutical molecules with imidazole derived heterocycles.

A transition metal-free cascade reaction using heterogeneous tin(IV)oxide catalyzed and iodine promoted synthesis of 3-aroylimidazo[1,2-a]pyridines

The cascade synthesis of 3-aroylimidazo[1,2-a]pyridines using chalcones and 2-aminopyridine was achieved over the SnO2/I2 catalytic system in toluene at ambient air atmosphere. The catalyst shows high activity towards the broad subst

Superparamagnetic nanoparticle-catalyzed coupling of 2-amino pyridines/pyrimidines with trans-chalcones

An aerobic coupling of 2-aminopyrimidines or 2-aminopyridines with trans-chalcones to afford aroylimidazo[1,2-a]pyrimidines and aroylimidazo[1,2-a]pyridines is reported. Reactions proceed in the presence of CuFe2O4 superparamagnetic

Copper-Catalyzed C-N Bond Formation via C-H Functionalization: Facile Synthesis of Multisubstituted Imidazo[1,2- a ]pyridines from N -(2-Pyridinyl)enaminones

An efficient, new copper-catalyzed approach to the construction of the multisubstituted imidazo[1,2- a ]pyridine skeleton from N -(2-pyridinyl)enaminones has been developed.

Iodine-promoted oxidative coupling reaction: a simple and efficient process to access imidazo[1,2-a]pyridines from 2-aminopyridines and chalcones

A unique and efficient approach has been developed for the synthesis of substituted imidazo[1,2-a]pyridines with aminopyridines and chalcones via a one-pot I2-induced aerobic oxidative coupling. The reported reaction proceeded though a tandem Michael addition followed by an intramolecular oxidative amination with high regioselectivity, yields and good functional group tolerance.

Iodine/Copper Iodide-Mediated C-H Functionalization: Synthesis of Imidazo[1,2-a]pyridines and Indoles from N-Aryl Enamines

A practical intramolecular C-H functionalization reaction of N-aryl enamines has been carried out with molecular iodine (I2) as the sole oxidant in the presence of copper iodide (CuI). The efficient and versatile synthetic method described here

Copper-catalyzed intramolecular oxidative amination of enaminone C-H bond for the synthesis of imidazo[1,2-a]pyridines

The intramolecular C-N bond forming cross coupling reactions on the enaminones has been achieved for the synthesis of imidazole[1,2-a]pyridines via copper-catalyzed C(sp2)-H amination. This protocol provides a new route for the synthesis of 2-u

Copper catalyzed aerobic oxidative cyclization and ketonization: One pot synthesis of benzoimidazo[1,2-: A] imidazolones

A highly efficient synthesis of benzoimidazo[1,2-a]imidazolone through a novel oxidative 5-exo-dig cyclization-ketonization cascade of 2-aminobenzimidazole, aldehyde and terminal alkyne has been explored under aerobic conditions. The reaction proceeds thr

CBr4 Mediated Oxidative C-N Bond Formation: Applied in the Synthesis of Imidazo[1,2-α]pyridines and Imidazo[1,2-α]pyrimidines

The carbon tetrabromide mediated oxidative carbon-nitrogen bond formation of 2-aminopyridines or 2-aminopyrimidines with β-keto esters or 1,3-diones, leading to a variety of complex imidazo[1,2-α]pyridines or imidazo[1,2-α]pyrimidines, is reported. The re

Copper supported on H+-modified manganese oxide octahedral molecular sieves (Cu/H-OMS-2) as a heterogeneous biomimetic catalyst for the synthesis of imidazo[1,2-a]-N-heterocycles

Copper supported on acid-modified manganese oxide octahedral molecular sieves (Cu/H-OMS-2) was prepared and found to be a versatile catalyst for the oxidative synthesis of 3-aroylimidazopyridines with a broad substrate scope. Cu/H-OMS-2 that was character