61150-99-0Relevant academic research and scientific papers
TLR7/8 ANTAGONISTS AND USES THEREOF
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Paragraph 0082-0083, (2022/02/06)
The present invention relates to compounds of the invention and pharmaceutically acceptable compositions thereof, useful as TLR7/8 antagonists.
Preparation and NMR characterization of hydrogen bonding in 2- and 2,6-bis-(N,N-diethylaminomethyl)-4R-phenols
Brycki, Bogumil,Maciejewska, Hanna,Brzezinski, Bogumil,Zundel, Georg
, p. 61 - 71 (2007/10/02)
A series of Mannich mono- and di-bases derived from 4-substituted phenols were prepared and investigated by 1H and 13C NMR spectroscopy in chloroform-d1 solution.The chemical shifts of intramolecular hydrogen-bonded protons in Mannich bases depend on the
Potential Antimalarials. VII. Di-Mannich Bases of 4-aminophenol via 4-Nitrophenols
Barlin, Gordon B.,Ireland, Stephen J.
, p. 1727 - 1734 (2007/10/02)
A series of di-Mannich bases have been prepared from 4-nitrophenol and paraformaldehyde with dimethylamine, diethylamine, dipropylamine, N-(2'-hydroxyethyl)methylamine, piperidine, 3- and 4-methylpiperidine, 3,5-dimethylpiperidine or pyrrolidine.These nit
