612068-44-7

Basic information

• Product Name: N-[2-(1,4-dioxaspiro[4,5]dec-7-en-8-yl)-ethyl]-2-iodo-4-methoxybenzamide
• Synonyms: N-[2-(1,4-dioxaspiro[4,5]dec-7-en-8-yl)-ethyl]-2-iodo-4-methoxybenzamide
• CAS NO: 612068-44-7
• Molecular Weight: 443.281
• Mol File: 612068-44-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[2-(1,4-dioxaspiro[4,5]dec-7-en-8-yl)-ethyl]-2-iodo-4-methoxybenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-(1,4-dioxaspiro[4,5]dec-7-en-8-yl)-ethyl]-2-iodo-4-methoxybenzamide(612068-44-7)
• EPA Substance Registry System: N-[2-(1,4-dioxaspiro[4,5]dec-7-en-8-yl)-ethyl]-2-iodo-4-methoxybenzamide(612068-44-7)

Safety Data

• Hazardous Substances Data: 612068-44-7(Hazardous Substances Data)

Upstream product

• 612068-36-7 2-[2-(8-hydroxy-1,4-dioxaspiro[4,5]dec-8-yl)-ethyl]-isoindole-1,3-dione 
• 612068-37-8 2-[2-(1,4-dioxaspiro[4,5]dec-7-en-8-yl)-ethyl]-isoindole-1,3-dione 
• 189509-22-6 (8-hydroxy-1,4-dioxaspiro[4,5]dec-8-yl)-acetic acid ethyl ester 
• 189509-23-7 8-(2-hydroxyethyl)-1,4-dioxaspiro[4,5]decan-8-ol 
• 123-11-5 4-methoxy-benzaldehyde 
• 2186-92-7 p-Anisaldehyde dimethyl acetal 
• 4746-97-8 cyclohexanedione monoethylene ketal 
• 612068-38-9 2-(1,4-dioxaspiro[4,5]dec-7-en-8-yl)-ethylamine 
• 54435-09-5 2-iodo-4-methoxybenzoic acid 
• 105469-13-4 2-iodo-4-methoxybenzaldehyde 

Downstream Products

• 612068-45-8 N-[2-(1,4-dioxaspiro[4,5]dec-7-en-8-yl)-ethyl]-2-iodo-4-methoxy-N-methylbenzamide 

Relevant articles and documents

Synthesis of galanthamine analogs as acetylcholinesterase inhibitors via intramolecular heck cvclization

A novel approach towards the construction of the galanthamine skeleton was demonstrated by the Pdcatalyzed cyclization of N-[2-(l,4-dioxa-spiro[4,5]dec-7- en-8-yl)-ethyl]-2-iodo-4-methoxy-N-methylbenzamide (23), with formation of the benzazepine ring and creation of a quaternary carbon.