61260-46-6Relevant academic research and scientific papers
One-Pot Synthesis of Tertiary Amides from Organic Trichlorides through Oxygen Atom Incorporation from Air by Convergent Paired Electrolysis
Luo, Zhongli,Imamura, Kenji,Shiota, Yoshihito,Yoshizawa, Kazunari,Hisaeda, Yoshio,Shimakoshi, Hisashi
, p. 5983 - 5990 (2021/05/04)
A convergent paired electrolysis catalyzed by a B12 complex for the one-pot synthesis of a tertiary amide from organic trichlorides (R-CCl3) has been developed. Various readily available organic trichlorides, such as benzotrichloride and its derivatives, chloroform, dichlorodiphenyltrichloroethane (DDT), trichloro-2,2,2-trifluoroethane (CFC-113a), and trichloroacetonitrile (CNCCl3), were converted to amides in the presence of tertiary amines through oxygen incorporation from air at room temperature. The amide formation mechanism in the paired electrolysis, which was mediated by a cobalt complex, was proposed.
RuO4-mediated oxidation of tertiary amines. stereoelectronic effects
Petride, Horia,Florea, Cristina,H?rtopeanu, Anca,Stavarache, Cristina
, p. 89 - 96 (2021/02/05)
Tertiary amines like PhCH2-NMe-CH2R (R = H, Me, CN) underwent RuO4-mediated oxidation by attack at all three N-α-positions. The various reaction products were classified in three groups, according to the functionalized sit
Oxidation of benzylamines to amides
Markgraf, J. Hodge,Sangani, Poorab K.,Finkelstein, Manuel
, p. 1285 - 1290 (2007/10/03)
A convenient method for the conversion of tertiary benzylamines to benzamides by phase transfer oxidation is described. Yields are good. Regioselectivities are reported.
