623938-46-5Relevant academic research and scientific papers
Enantioselective Aza-Heck Cyclizations of N-(Tosyloxy)carbamates: Synthesis of Pyrrolidines and Piperidines
Ma, Xiaofeng,Hazelden, Ian R.,Langer, Thomas,Munday, Rachel H.,Bower, John F.
, p. 3356 - 3360 (2019/03/07)
Pd(0)-systems modified with SPINOL-derived phosphoramidate ligands promote highly enantioselective aza-Heck cyclizations of alkenyl N-(tosyloxy)carbamates. The method provides versatile access to challenging N-heterocycles and represents the broadest scope enantioselective aza-Heck protocol developed to date.
Gold(I)-catalyzed enantioselective intramolecular dehydrative amination of allylic alcohols with carbamates
Mukherjee, Paramita,Widenhoefer, Ross A.
supporting information; experimental part, p. 1405 - 1407 (2012/03/11)
Aliphatic nitrogen heterocycles either five- or six-membered are formed in high yield and with up to 94 %ee when a 1:2 mixture of [(S)-2](AuCl)2 and AgClO4 is used as the catalyst for the title reaction. Copyright
Highly chiral muscarinic ligands: The discovery of (2S,2′R,3′S, 5′R)-1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine 3-sulfoxide methyl iodide, a potent, functionally selective, M2 partial agonist
Scapecchi, Serena,Matucci, Rosanna,Bellucci, Cristina,Buccioni, Michela,Dei, Silvia,Guandalini, Luca,Martelli, Cecilia,Manetti, Dina,Martini, Elisabetta,Marucci, Gabriella,Nesi, Marta,Romanelli, Maria Novella,Teodori, Elisabetta,Gualtieri, Fulvio
, p. 1925 - 1931 (2007/10/03)
By further steric complication of previously studied highly chiral muscarinic agonists, we have obtained a small chiral library of enantiomeric and diasteromeric 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine 3-sulfoxides. Binding studies on cloned
Synthesis and cholinergic affinity of diastereomeric and enantiomeric isomers of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)- pyrrolidine, 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine and of Their iodomethylates
Dei, Silvia,Bellucci, Cristina,Buccioni, Michela,Ferraroni, Marta,Gualtieri, Fulvio,Guandalini, Luca,Manetti, Dina,Matucci, Rosanna,Romanelli, Maria Novella,Scapecchi, Serena,Teodori, Elisabetta
, p. 3153 - 3164 (2007/10/03)
Four out of the eight possible stereoisomers of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine, 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine and the corresponding iodomethylates have been synthesised. They were formally derived from hybridisat
