61365-94-4Relevant articles and documents
Arylation of azlactones using diaryliodonium bromides and silver carbonate: Facile access to α-tetrasubstituted amino acid derivatives
Chai, Zhuo,Wang, Biao,Chen, Jia-Nan,Yang, Gaosheng
, p. 2714 - 2718 (2014)
With the combined use of silver carbonate, diaryliodonium bromides were successfully utilized as aryl source to realize the highly efficient arylation of azlactones under mild conditions. The reaction worked well with various alkyl- and aryl-substituted azlactones, providing a range of α-tetrasubstituted amino acid derivatives in moderate to high yields.
Palladium-catalyzed alpha-arylation of azlactones to form quaternary amino acid derivatives.
Liu, Xiaoxiang,Hartwig, John F
, p. 1915 - 1918 (2007/10/03)
[reaction: see text] The synthesis of alpha-aryl-alpha-alkyl amino acid derivatives from alpha-amino acids by the arylation of azlactone derivatives is reported. Arylation of azlactones derived from alanine, valine, phenalanine, phenyl glycine, and leucin
