613671-69-5Relevant academic research and scientific papers
Novel Kn?evenagel-type reaction via titanium enolate derived from Ti(O-i-Pr)4 and diketene
Hayashi, Masahiko,Nakamura, Norihiro,Yamashita, Kohei
, p. 6777 - 6783 (2004)
Kn?evenagel-type reaction between diketene and aldehydes proceeded in the presence of Ti(O-i-Pr)4. This reaction proceeded via titanium enolate derived from Ti(O-i-Pr)4 and diketene. As for the stereoselectivity of the products, E-is
Glucose-lowering in a db/db mouse model by dihydropyridine diacid glycogen phosphorylase inhibitors
Ogawa, Anthony K.,Willoughby, Chris A.,Bergeron, Raynald,Ellsworth, Kenneth P.,Geissler, Wayne M.,Myers, Robert W.,Yao, Jun,Harris, Georgianna,Chapman, Kevin T.
, p. 3405 - 3408 (2007/10/03)
The synthesis of a series of novel dihdyropyridine diacid glycogen phosphorylase inhibitors is presented. SAR and functional assay data are discussed, along with the effect of a single inhibitor on blood glucose in a diabetic animal model.
