61369-32-2Relevant academic research and scientific papers
Substrate- and base-dependent reactivities of acylketene toward aryl aldimines derived from 2-amino-4-methylpyridine
Ocal, Nuket,Mor, Necla,Erden, Ihsan
, p. 6468 - 6471 (2015/11/16)
Acylketene, generated from 2,2,6-trimethyl-4H-1,3-dioxin-4-one reacts with aryl aldimines derived from 4-methyl-2-aminopyridine to give a variety of products, depending on the substituent on the C-aryl group, base used, and hydrolytic stability of the starting aldimine. Also the presence of the N-(2-pyridyl) group plays an important role in the fate of the reaction course, frequently participating in intramolecular conjugate additions, giving rise to interesting heterocycles.
1,3-Oxazines and Related Compounds. XIV. Facile Synthesis of 2,3,6-Trisubstituted 2,3-Dihydro-1,3-oxazine-5-carboxilyc Acids and 1,4-Disubstituted 3-Acyl-β-lactams from Acyl Meldrum's Acids and Schiff Bases
Yamamoto, Yutaka,Watanabe, Yokiyoshi
, p. 1871 - 1879 (2007/10/02)
Simple preparation of 2,3,6trisubstituted 2,3-dihydro-1,3-oxazine-5-carboxylic acids (4) and 1,4-disubstituted 3-acyl-β-lactams (5) from acyl Meldrum's acids and Schiff bases were carried out.2,3-Disubstituted 5-acyl-3,4,5,6-tetrahydro-2H-1,3-oxazine-4,6-
1,3-Oxazines and Related Compounds. XIII. Reaction of Acyl Meldrum's Acids with Schiff Bases Giving 2,3-Disubstituted 5-Acyl-3,4,5,6-tetrahydro-2H-1,3-oxazine-4,6-diones and 2,3,6-Trisubstituted 2,3-Dihydro-1,3-oxazin-4-ones
Yamamoto, Yutaka,Watanabe, Yukiyoshi,,Ohnishi, Shuhei
, p. 1860 - 1870 (2007/10/02)
The reaction of Schiff bases (2) with various acyl Meldrum's acids (1) were investigated.Refluxing of 1 and 2 in benzene caused an exchange reaction of the acetone moiety of 1 with the Schiff base moiety through the intermediate acylketenes 11 formed in s
Reaction of 2,2,6-trimethyl-1,3-dioxin-4-one with Imines
Masayuki, Sato,Ogasawara, Hiromichi,Yoshizumi, Eriko,Kato, Tetsuzo
, p. 1902 - 1909 (2007/10/02)
The reaction of 2,2,6-trimethyl-1,3-dioxin-4-one (diketene-acetone adduct) (1) with imines was investigated.Heating of the adduct 1 with N-(1-phenylethylidene)aniline (6a) gave 6-methyl-1,2-diphenyl-4(1H)-pyridone 7a.Similar treatment of N-benzylideneanil
