6139-83-9 Usage
Uses
Used in Pharmaceutical Industry:
4-Chlorobutanal diethyl acetal is used as a key intermediate in the synthesis of Sumatriptan, Rizatriptan, Almotriptan, and Zolmitriptan. These are medications belonging to the triptan class, which are primarily used for the acute treatment of migraine headaches and cluster headaches. 4-Chlorobutanal diethyl acetal plays a crucial role in the production process, enabling the formation of the final drug molecules.
Used in Organic Synthesis:
4-Chlorobutanal diethyl acetal is also used in the preparation of Fendiline derivatives, which are KRAS modulators. KRAS proteins are involved in cell signaling pathways and are often mutated in various types of cancer. Fendiline derivatives have the potential to target and modulate the activity of KRAS proteins, offering a promising avenue for the development of cancer therapeutics.
Check Digit Verification of cas no
The CAS Registry Mumber 6139-83-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,1,3 and 9 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 6139-83:
(6*6)+(5*1)+(4*3)+(3*9)+(2*8)+(1*3)=99
99 % 10 = 9
So 6139-83-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H17ClO2/c1-3-10-8(11-4-2)6-5-7-9/h8H,3-7H2,1-2H3
6139-83-9Relevant academic research and scientific papers
Process for preparing derivatives of 4-halobutyraldehyde
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Page 3-4, (2008/06/13)
The present invention describes a process for preparing an enol ester of a 4-halo-butyraldehyde which comprises contacting a cyclopropane carboxaldehyde (CPCA) and a carboxylic acid halide in the presence of a Lewis acid catalyst. In addition, the present invention relates to a process for preparing an acetal of a 4-halo-butyraldehyde which comprises contacting an enol ester of a 4-halo-butyraldehyde, prepared according to the present invention, with an alcohol in the presence of a certain acid catalyst.
Diesters of 6-cyano-2,2-tetrahydropyrandicarboxylates
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, (2008/06/13)
A compound of the formula STR1 wherein R' is lower alkyl, is useful as an intermediate in the preparation of a corresponding tricarboxylate, which is a useful detergent builder.
