614-14-2

Basic information

• Product Name: 1-PHENYL-1-BUTANOL
• Synonyms: 1-Butanol, 1-phenyl;1-phenyl-butan-1-ol;1-phenylbutan-1-ol;Benzenemethanol, alpha-propyl-;A-PROPYLBENZYL ALCOHOL;AURORA KA-6946;ALPHA-PROPYLBENZYL ALCOHOL;1-PHENYL-1-BUTANOL
• CAS NO: 614-14-2
• Molecular Formula: C₁₀H₁₄O
• Molecular Weight: 150.22
• EINECS: 210-368-6
• Mol File: 614-14-2.mol
• Article Data: 167

Chemical Properties

• Melting Point: 16 °C
• Boiling Point: 170 °C / 100mmHg
• Appearance: /
• Density: 0.98
• Refractive Index: 1.5120 to 1.5160
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: DCM, Methanol
• CAS DataBase Reference: 1-PHENYL-1-BUTANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-PHENYL-1-BUTANOL(614-14-2)
• EPA Substance Registry System: 1-PHENYL-1-BUTANOL(614-14-2)

Safety Data

• Hazardous Substances Data: 614-14-2(Hazardous Substances Data)

Usage

Uses

1-Phenyl-1-butanol is an intermediate in the synthesis of (E)-1-Phenyl-1-butene (P319495), a compound used to study olefin oxidation by cytochrome P-450.

InChI:InChI=1/C10H14O/c1-2-6-10(11)9-7-4-3-5-8-9/h3-5,7-8,10-11H,2,6H2,1H3

Upstream product

• 123-91-1 1,4-dioxane 
• 91-01-0 1,1-Diphenylmethanol 
• 556-91-2 aluminum tri-tert-butoxide 
• 495-40-9 propiophenone 
• 64-17-5 ethanol 
• 1007-32-5 benzyl ethyl ketone 
• 591-50-4 iodobenzene 
• 624-31-7 4-tolyl iodide 
• 100-52-7 benzaldehyde 
• 834-15-1 bis(p-tolyl)telluride 
• 5395-43-7 tri(p-tolyl)antimony 
• 5142-75-6 tri(p-tolyl)bismuth 
• 136-60-7 benzoic acid, butyl ester 
• 2372-45-4 sodium butanolate 

Downstream Products

• 119-61-9 benzophenone 
• 91-01-0 1,1-Diphenylmethanol 
• 495-40-9 propiophenone 
• 5702-42-1 5-ethyl-4-phenyl-[1,3]dioxane 
• 824-90-8 1-phenylbut-1-ene 
• 27059-40-1 (1-chlorobutyl)benzene 
• 84473-31-4 4-(Bromobutyl)benzene 
• 1005-64-7 trans-1-phenyl-1-butene 
• 58687-89-1 1-phenyl-1-butylhydroperoxide 
• 91491-80-4 (+/-)-phthalic acid mono-(1-phenyl-butyl ester) 
• 58687-90-4 (α-benzoyloxybutyl)benzene 
• 86561-24-2 (RS)-1-phenyl-1-butanol acetate 
• 7476-99-5 1-phenylbutyl butyrate 
• 119994-30-8 [1]naphthyl-carbamic acid-(1-phenyl-butyl ester) 

Relevant articles and documents

Zirconium-catalyzed cyclopropanation of α-olefins mediated by R′CO2R″ and ClnAlEt3-n

A Cp2ZrCl2-catalyzed one-pot cyclopropanation method has been developed to afford alkoxycyclopropanes and cyclopropanols from α-olefins involving esters of carboxylic acids and ClnAlEt 3-n.

Pincerlike molybdenum complex and preparation method thereof, catalytic composition and application thereof, and alcohol preparation method

The invention discloses a clamp-type molybdenum complex, a preparation method, a corresponding catalyst composition and application. The method comprises the steps: obtaining 9 molybdenum complexes with different structures through coordination reaction of 2-(substituent ethyl)-(5, 6, 7, 8-tetrahydroquinolyl) amine and a corresponding carbonyl molybdenum metal precursor; and catalyzing a ketone compound transfer hydrogenation reaction through a molybdenum complex to generate 40 alcohol compounds. The preparation method of the molybdenum complex is simple, high in yield and good in stability. For a transfer hydrogenation reaction of ketone, the molybdenum-based catalytic system has high catalytic activity and small molybdenum loading capacity, is used for production of aromatic and aliphatic alcohols, and has the advantages of simple method, small environmental pollution and high yield.

Method for synthesizing secondary alcohol in water phase

The invention discloses a method for synthesizing secondary alcohol in a water phase. The method comprises the following steps: taking ketone as a raw material, selecting water as a solvent, and carrying out catalytic hydrogenation reaction on the ketone in the presence of a water-soluble catalyst to obtain the secondary alcohol, wherein the catalyst is a metal iridium complex [Cp * Ir (2, 2'-bpyO)(OH)][Na]. Water is used as the solvent, so that the use of an organic solvent is avoided, and the method is more environment-friendly; the reaction is carried out at relatively low temperature and normal pressure, and the reaction conditions are mild; alkali is not needed in the reaction, so that generation of byproducts is avoided; and the conversion rate of the raw materials is high, and the yield of the obtained product is high. The method not only has academic research value, but also has a certain industrialization prospect.

Visible Light Induced Reduction and Pinacol Coupling of Aldehydes and Ketones Catalyzed by Core/Shell Quantum Dots

We present an efficient and versatile visible light-driven methodology to transform aryl aldehydes and ketones chemoselectively either to alcohols or to pinacol products with CdSe/CdS core/shell quantum dots as photocatalysts. Thiophenols were used as proton and hydrogen atom donors and as hole traps for the excited quantum dots (QDs) in these reactions. The two products can be switched from one to the other simply by changing the amount of thiophenol in the reaction system. The core/shell QD catalysts are highly efficient with a turn over number (TON) larger than 4 × 104 and 4 × 105 for the reduction to alcohol and pinacol formation, respectively, and are very stable so that they can be recycled for at least 10 times in the reactions without significant loss of catalytic activity. The additional advantages of this method include good functional group tolerance, mild reaction conditions, the allowance of selectively reducing aldehydes in the presence of ketones, and easiness for large scale reactions. Reaction mechanisms were studied by quenching experiments and a radical capture experiment, and the reasons for the switchover of the reaction pathways upon the change of reaction conditions are provided.