6140-13-2Relevant articles and documents
Searching new structural scaffolds for BRAF inhibitors. An integrative study using theoretical and experimental techniques
Campos, Ludmila E.,Garibotto, Francisco M.,Angelina, Emilio,Kos, Jiri,Toma?i?, Tihomir,Zidar, Nace,Kikelj, Danijel,Gonec,Marvanova, Pavlina,Mokry, Petr,Jampilek,Alvarez, Sergio E.,Enriz, Ricardo D.
, (2019/08/12)
The identification of the V600E activating mutation in the protein kinase BRAF in around 50% of melanoma patients has driven the development of highly potent small inhibitors (BRAFi) of the mutated protein. To date, Dabrafenib and Vemurafenib, two specifi
Synthesis of Carbamates Using Yttria-Zirconia Based Lewis Acid Catalyst
Pandey, Rajesh K.,Dagade, Sharda P.,Dongare, Mohan K.,Kumar, Pradeep
, p. 4019 - 4027 (2007/10/03)
A variety of amines react with chloroformates in the presence of catalytic amount of yttria-zirconia based catalyst to afford the corresponding carbamates in excellent yields.
Cyclic guanidines. IX. Synthesis of 2-amino-3,4-dihydroquinazolines as blood platelet aggregation inhibitors.
Ishikawa,Watanabe,Saegusa
, p. 1357 - 1364 (2007/10/02)
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