61425-17-0

Usage

Uses

Nocardicin D is a β-lactam antibiotic.

InChI:InChI=1/C23H23N3O9/c24-16(22(31)32)9-10-35-15-7-3-13(4-8-15)19(28)20(29)25-17-11-26(21(17)30)18(23(33)34)12-1-5-14(27)6-2-12/h1-8,16-18,27H,9-11,24H2,(H,25,29)(H,31,32)(H,33,34)/t16-,17+,18-/m1/s1

Upstream product

• 67529-87-7 -propoxy>phenyl>glyoxylic acid 
• 88147-50-6 (αR,3S)-3-amino-α-(p-hydroxyphenyl)-2-oxo1-azetidine-acetic acid Na salt 
• 110207-51-7 di-tert-butyl N-(tert-butoxycarbonyl)nocardicin D 
• 4397-53-9 p-benzyloxybenzaldehyde 
• 88147-47-1 (3R)-α--3-bromo-N-(diphenylmethyl)-2-oxo-1-azetidineacetamide 
• 88147-53-9 4-Chloro-benzenesulfonic acid (R)-1-[(benzhydryl-carbamoyl)-(4-benzyloxy-phenyl)-methyl]-2-oxo-azetidin-3-yl ester 
• 73888-92-3 diphenylmethyl D-4-(p-acetylphenoxy)-2-(1-t-butoxyformamido)butyrate 
• 88147-46-0 (3S)-α-<(p-benzyloxy)phenyl>-N-(diphenylmethyl)-3-hydroxy-2-oxo-1-azedineacetamide 
• 88147-49-3 diphenylmethyl (αR,3S)-3-azido-α--2-oxo-1-azetidineacetate 
• 38250-16-7 4-hydroxy-alpha-oxobenzeneacetic acid methyl ester 
• 110207-53-9 <4--3-(tert-butoxycarbonyl)propoxy>benzoyl>formic acid 
• 110207-50-6 methyl <4--3-(tert-butoxycarbonyl)propoxy>benzoyl>formate 
• 54537-30-3 p-hydroxybenzoylformic acid sodium salt 
• 123004-73-9 (-)-tert-butyl 3-aminonocardicinate hydrochloride 

Downstream Products

• 61365-37-5 (R)-2-Amino-4-(4-{((S)-1-carboxy-2-{[(R)-carboxy-(4-hydroxy-phenyl)-methyl]-amino}-ethylcarbamoyl)-[(Z)-hydroxyimino]-methyl}-phenoxy)-butyric acid 

Relevant academic research and scientific papers

Total syntheses of (-)-nocardicins A-G: A biogenetic approach

The known nocardicins A-G have been synthesized, several for the first time, having geometric and stereoisomeric purities of a high order. The syntheses proceed through the central intermediacy of tert-butyl (-)-3-aminocardicinate (14), which has been pre

A total synthesis of nocardicins

Four-component-condensation of D-isoserine or L-isoserine, diphenylmethyl isocyanide and p-(benzyloxy)benzaldehyde was used to construct a functionalized β-lactam ring system which was transformed in 4 steps into 3-aminocardicinic acid. A protected side c