61440-63-9Relevant academic research and scientific papers
Microenvironment response type cross-linked quaternary ammonium salt micelle antibacterial agent and preparation method and application thereof
-
, (2019/05/23)
The invention discloses a microenvironment response type cross-linked quaternary ammonium salt micelle antibacterial agent and a preparation method and application thereof, and belongs to the field ofbiomedical materials. Crosslinked micelles can well pen
Rational Design of Supramolecular Dynamic Protein Assemblies by Using a Micelle-Assisted Activity-Based Protein-Labeling Technology
Sandanaraj, Britto S.,Reddy, Mullapudi Mohan,Bhandari, Pavankumar Janardhan,Kumar, Sugam,Aswal, Vinod K.
supporting information, p. 16085 - 16096 (2018/10/15)
The self-assembly of proteins into higher-order superstructures is ubiquitous in biological systems. Genetic methods comprising both computational and rational design strategies are emerging as powerful methods for the design of synthetic protein complexes with high accuracy and fidelity. Although useful, most of the reported protein complexes lack a dynamic behavior, which may limit their potential applications. On the contrary, protein engineering by using chemical strategies offers excellent possibilities for the design of protein complexes with stimuli-responsive functions and adaptive behavior. However, designs based on chemical strategies are not accurate and therefore, yield polydisperse samples that are difficult to characterize. Here, we describe simple design principles for the construction of protein complexes through a supramolecular chemical strategy. A micelle-assisted activity-based protein-labeling technology has been developed to synthesize libraries of facially amphiphilic synthetic proteins, which self-assemble to form protein complexes through hydrophobic interaction. The proposed methodology is amenable for the synthesis of protein complex libraries with molecular weights and dimensions comparable to naturally occurring protein cages. The designed protein complexes display a rich structural diversity, oligomeric states, sizes, and surface charges that can be engineered through the macromolecular design. The broad utility of this method is demonstrated by the design of most sophisticated stimuli-responsive systems that can be programmed to assemble/disassemble in a reversible/irreversible fashion by using the pH or light as trigger.
Solvent-free thiophene-based electrolytes: synthesis of new liquid-crystalline ionic conductors for batteries: part I
Bogdanowicz, Krzysztof Artur,Gancarz, Pawel,Filapek, Michal,Pociecha, Damian,Marzec, Monika,Chojnacka, Ida,Iwan, Agnieszka
, p. 15714 - 15724 (2018/11/23)
New liquid crystalline thiophene esters, thiophene-3-yl 3,4,5-tris(n-dodecan-1-yloxy)benzoate (ThBz1) and thiophene-3-yl 3,4,5-tris[4-(n-dodecan-1-yloxy)benzyloxy]benzoate (ThBz2), were synthesized for use in lithium-ion batteries as safe, new solvent-fre
COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE
-
Page/Page column 77-78, (2018/02/28)
This invention relates to compounds and compositions for the induction of expression of a pattern recognition receptor (e.g., STING) and methods of use thereof.
COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE
-
Page/Page column 68-69, (2018/03/25)
This invention relates to compounds and compositions for the induction of expression of a pattern recognition receptor (e.g., STING) and methods of use thereof.
HYDROPHOBIN MIMICS: PROCESS FOR PREPARATION THEREOF
-
Paragraph 01112; 0113; 0165; 0166; 0167; 0168; 0169; 0170, (2017/09/02)
The present invention discloses hydrophobin mimics of formula (I) comprising a protein head group, hydrophilic linker and hydrophobic tail and to a process for synthesis of library of hydrophobin mimics thereof. The hydrophobin mimics of the present invention self-assemble to form protein nanoparticles/nanocontainer either alone or in a specified chemical environment. The hydrophobin mimics (I) of the present invention find application in area of bio-nanotechnology.
POLYCATENAR LIGANDS AND HYBRID NANOPARTICLES MADE THEREFROM
-
Page/Page column 35; 36; 37; 41, (2017/10/13)
Described herein are polycatenar ligand compounds and their use in the production of hybrid nanoparticles, typically nanocrystals. The present disclosure also relates to films containing the hybrid nanoparticles described herein and their use.
Nanoparticles and nanoparticle compositions
-
, (2016/06/01)
The invention provides multivalent surface-crosslinked micelle (SCM) particles, crosslinked reverse micelle (CRM) particles, and methods of making and using them. The SCM particles can be used, for example, to inhibit a virus or bacteria from binding to a host cell. The inhibition can be used in therapy for the flu, cancer, or AIDS. The CRM particles can be used, for example, to prepare metal nanoparticles or metal alloy nanoparticles, or they can be used in catalytic reactions.
Polycatenar Ligand Control of the Synthesis and Self-Assembly of Colloidal Nanocrystals
Diroll, Benjamin T.,Jishkariani, Davit,Cargnello, Matteo,Murray, Christopher B.,Donnio, Bertrand
supporting information, p. 10508 - 10515 (2016/09/04)
Hydrophobic colloidal nanocrystals are typically synthesized and manipulated with commercially available ligands, and surface functionalization is therefore typically limited to a small number of molecules. Here, we report the use of polycatenar ligands d
Luminescent columnar liquid crystals based on 1,3,4-oxadiazole
Girotto, Edivandro,Eccher, Juliana,Vieira, André A.,Bechtold, Ivan H.,Gallardo, Hugo
, p. 3355 - 3360 (2014/05/06)
In this study five new compounds, derivatives of 1,3,4-oxadiazole, were synthesized in order to achieve mesomorphic behavior and luminescence. Different types of aliphatic chains were used in order to investigate the influence of alkoxide groups in mesomorphic behavior. All of the compounds showed high thermal stability and strong blue photoluminescence in solution and in solid films. Furthermore, compounds 10a-d presented hexagonal columnar mesomorphism, which was characterized by polarizing optical microscopy and X-ray diffraction, and strong π-stacking was observed. Notably, for two compounds (10c,d), the liquid crystal properties were preserved on cooling from the isotropic state to room temperature. These characteristics make these materials good candidates for application in organic electronics.
