61451-86-3Relevant articles and documents
Rhodium catalysts derived from a fluorinated phanephos ligand are highly active catalysts for direct asymmetric reductive amination of secondary amines
Gilbert, Sophie H.,Tin, Sergey,Fuentes, José A.,Fanjul, Tamara,Clarke, Matthew L.
supporting information, (2021/01/14)
An asymmetric hydrogenation of enamines is efficiently catalysed by rhodium complexed with a fluorinated version of the planar chiral paracyclophane-diphosphine ligand, Phanephos. This catalyst was shown to be very active, with examples operating at just
Chiral molecular tweezers: Synthesis and reactivity in asymmetric hydrogenation
Lindqvist, Markus,Borre, Katja,Axenov, Kirill,Kótai, Bianka,Nieger, Martin,Leskel?, Markku,Pápai, Imre,Repo, Timo
supporting information, p. 4038 - 4041 (2015/04/14)
We report the synthesis and reactivity of a chiral aminoborane displaying both rapid and reversible H2 activation. The catalyst shows exceptional reactivity in asymmetric hydrogenation of enamines and unhindered imines with stereoselectivities of up to 99% ee. DFT analysis of the reaction mechanism pointed to the importance of both repulsive steric and stabilizing intermolecular non-covalent forces in the stereodetermining hydride transfer step of the catalytic cycle.
Borrowing hydrogen methodology for amine synthesis under solvent-free microwave conditions
Watson, Andrew J. A.,Maxwell, Aoife C.,Williams, Jonathan M. J.
supporting information; experimental part, p. 2328 - 2331 (2011/05/17)
Application of microwave heating to the Borrowing Hydrogen strategy to form C-N bonds from alcohols and amines is presented, removing the need for solvent and reducing the reaction times while still yielding results comparable with those using thermal heating.
