61463-61-4Relevant academic research and scientific papers
MIDA boronate allylation-synthesis of ibuprofen
Brodie, Glen,France, David J.,Memarzadeh, Sarah,Phillips, David,Tang, Gi Lum
, p. 30624 - 30630 (2020/09/11)
MIDA boronates are among the most useful reagents for the Suzuki-Miyaura reaction. This chemistry typically generates new bonds between two aromatic rings, thereby restricting access to important areas of chemical space. Here we demonstrate the coupling of MIDA boronates to allylic electrophiles, including a new synthesis of the well-known COX inhibitor ibuprofen. This journal is
Photo-Ni-Dual-Catalytic C(sp2)-C(sp3) Cross-Coupling Reactions with Mesoporous Graphitic Carbon Nitride as a Heterogeneous Organic Semiconductor Photocatalyst
Antonietti, Markus,Ghosh, Indrajit,K?nig, Burkhard,Khamrai, Jagadish,Savateev, Aleksandr
, p. 3526 - 3532 (2020/04/09)
The synergistic combination of a heterogeneous organic semiconductor mesoporous graphitic carbon nitride (mpg-CN) and a homogeneous nickel catalyst with visible-light irradiation at room temperature affords the C(sp2)-C(sp3) cross-co
One-pot Construction of Difluorinated Pyrrolizidine and Indolizidine Scaffolds via Copper-Catalyzed Radical Cascade Annulation
Wang, Xiaoyang,Li, Miao,Yang, Yanyan,Guo, Minjie,Tang, Xiangyang,Wang, Guangwei
supporting information, p. 2151 - 2156 (2018/04/26)
A convenient approach to the synthesis of diverse difluorinated nitrogen-containing polycycles via a copper-catalyzed radical cascade annulation of amine-containing olefins and ethyl bromodifluoroacetate was developed. Three new bonds, including a Csp3 ?CF2 and two C?N bonds, are forged simultaneously in this strategy. Through this strategy, a series of difluorinated pyrrolizidine and indolizidine derivatives have been conveniently synthesized in good yields. (Figure presented.).
Cross-Coupling Reactions of Aryldiazonium Salts with Allylsilanes under Merged Gold/Visible-Light Photoredox Catalysis
Akram, Manjur O.,Mali, Pramod S.,Patil, Nitin T.
supporting information, p. 3075 - 3078 (2017/06/23)
A method for the cross-coupling reactions of aryldiazonium salts with trialkylallylsilanes via merged gold/photoredox catalysis is described. The reaction is proposed to proceed through a photoredox-promoted generation of an electrophilic arylgold(III) intermediate that undergoes transmetalation with allyltrimethylsilane to form allylarenes.
Copper-Catalyzed Redox-Triggered Remote C-H Functionalization: Highly Selective Formation of C-CF3 and C-O Bonds
Li, Taotao,Yu, Peng,Lin, Jin-Shun,Zhi, Yonggang,Liu, Xin-Yuan
supporting information, p. 490 - 494 (2016/06/01)
A Cu-catalyzed remote sp3 C-H/unactivated alkenes functionalization reaction for the concomitant construction of C-CF3 and C-O bonds was described. An 1,5-H radical transfer involving an sp3 C-H bond adjacent to a nitrogen atom and an α-CF3-alkyl radical intermediate derived from unactivated alkenes was observed and demonstrated to proceed via the radical process. C-CF3 formation/1,5-H radical shift/remote functionalization of sp3 C-H bond.
Allyl-transfer reaction from photoexcited hypervalent allylsilicon reagent toward dicyanobenzenes
Matsuoka, Daisuke,Nishigaichi, Yutaka
supporting information, p. 163 - 165 (2015/02/19)
Photoreaction between dicyanobenzenes and a hypervalent allylsilicon reagent us ing 2,3-dihydroxynaphtha lene as a ligand on silicon efficiently proceeded to afford a llyl-substituted benzonitriles in moderate to good yields. The present photoreaction was
Phosphine-catalyzed remote β-C-H functionalization of amines triggered by trifluoromethylation of alkenes: One-pot synthesis of bistrifluoromethylated enamides and oxazoles
Yu, Peng,Zheng, Sheng-Cai,Yang, Ning-Yuan,Tan, Bin,Liu, Xin-Yuan
supporting information, p. 4041 - 4045 (2015/03/30)
An unprecedented phosphine-catalyzed remote β-C-H functionalization of amine derivatives triggered by trifluoromethylation of an alkene with Togni's reagent was disclosed. This reaction proceeded through the highly selective and concomitant activation of
Photosubstitution of dicyanoarenes by hypervalent allylsilicon reagents via photoinduced electron transfer
Matsuoka, Daisuke,Nishigaichi, Yutaka
, p. 559 - 561 (2014/04/17)
Photosubstitution of dicyanoarenes with hypervalent allylsilicon reagents in the presence of anthracene efficiently proceeded to afford the allyl-substituted product in moderate to good yields. The efficiency for the present photoreaction was much higher
Enantioselective C-H bond functionalization triggered by radical trifluoromethylation of unactivated alkene
Yu, Peng,Lin, Jin-Shun,Li, Lei,Zheng, Sheng-Cai,Xiong, Ya-Ping,Zhao, Li-Jiao,Tan, Bin,Liu, Xin-Yuan
supporting information, p. 11890 - 11894 (2015/02/05)
An asymmetric unactivated alkene/C-H bond difunctionalization reaction for the concomitant construction of C-CF3 and C-Obonds was realized by using a Cu/Bronsted acid cooperative catalytic system, thus providing facile access to valuable chiral
Palladium-catalyzed selective aminoamidation and aminocyanation of alkenes using isonitrile as amide and cyanide sources
Jiang, Huanfeng,Gao, Hanling,Liu, Bifu,Wu, Wanqing
supporting information, p. 15348 - 15351 (2015/01/08)
A mild and efficient palladium-catalyzed intermolecular aminoamidation and aminocyanation reaction of alkenes with a broad substrate scope has been developed. This cyclization process provides a valuable synthetic tool for obtaining substituted indolines, tetrahydroisoquinolines and pyrrolidines in good to excellent yields. This journal is
