61545-36-6

Usage

Uses

Used in Pharmaceutical Industry:
4-Benzyloxy-6-indole carboxylic acid methyl ester is used as a chemical intermediate for the synthesis of various pharmaceutical drugs and organic compounds. Its unique chemical structure allows it to be a key component in the development of new medicinal substances, contributing to advancements in drug discovery and innovation.
Used in Drug Synthesis:
As a chemical intermediate, 4-Benzyloxy-6-indole carboxylic acid methyl ester is utilized in the synthesis of a wide range of pharmaceutical drugs. Its versatile structure enables the creation of various organic compounds with potential therapeutic applications, making it an essential component in the development of new medications and treatments.
Used in Medicinal Substance Production:
4-Benzyloxy-6-indole carboxylic acid methyl ester is crucial for the production of various medicinal substances. Its presence in the synthesis process allows for the creation of compounds with specific therapeutic properties, contributing to the development of effective treatments for various medical conditions.

Upstream product

• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 187682-19-5 3-benzoyloxy-4-methyl-5-nitrobenzoic acid methyl ester 
• 125229-13-2 3-hydroxy-4-methyl-5-nitrobenzoic acid methyl ester 
• 100-44-7 benzyl chloride 
• 77140-48-8 4-hydroxy-1H-indole-6-carboxylic acid methyl ester 

Downstream Products

• 372100-55-5 4-benzyloxy-1-ethyl-1H-indole-6-carboxylic acid methyl ester 
• 187682-28-6 (2R,3S)-3-(4-Benzyloxy-3-formyl-6-methoxycarbonyl-indol-1-ylmethyl)-aziridine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester 
• 187682-21-9 4-Benzyloxy-3-formyl-1H-indole-6-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Chiral aziridinyl radicals: An application to the synthesis of the core nucleus of FR-900482

An asymmetric route to the core nucleus of the antitumor agent FR-900482 utilizes the cyclization of an aziridinyl radical into a functionalized indole nucleus. The route employs a selective Polonovski reaction and the Hootele-Dmitrienko rearrangement to install two oxygen atoms.

Aminopropanol substituted indole compounds and compositions for the treatment of cardiac and circulatory diseases

New aminopropanol compounds of the formula STR1 wherein R is lower alkyl, cycloalkyl or alkylthioalkyl, R1 is hydrogen or lower alkyl, hydroxyalkyl, pivaloyloxyalkyl, alkoxyalkyl, alkoxycarbonyl, carboxyl or --CONR3 R4, in which R3 and R4 which can be the same or different, represent hydrogen or lower alkyl, and R2 is lower alkyl, hydroxyalkyl, alkoxyalkyl or pivaloyloxyalkyl or, when R is alkylthioalkyl or R1 is pivaloyloxyalkyl, R2 can also be hydrogen and the pharmacologically acceptable salts thereof; are outstandingly effective in the treatment or prophylaxis of cardiac and circulatory diseases.

Aminopropanol compounds and compositions for the treatment of cardiac and circulatory diseases

New aminopropanol compounds of the formula STR1 wherein R is lower alkyl, cycloalkyl or alkylthioalkyl, R1 is hydrogen or lower alkyl, hydroxyalkyl, pivaloyloxyalkyl, alkoxyalkyl, alkoxycarbonyl, carboxyl or --CONR3 R4, in which R3 and R4 which can be the same or different, represent hydrogen or lower alkyl, and R2 is lower alkyl, hydroxyalkyl, alkoxyalkyl or pivaloyloxyalkyl or, when R is alkylthioalkyl or R1 is pivaloyloxyalkyl, R2 can also be hydrogen and The pharmacologically acceptable salts thereof; are outstandingly effective in the treatment or prophylaxis of cardiac and circulatory diseases.