61589-17-1

Basic information

• Product Name: ethyl 1-indolinecarboxylate
• Synonyms: ethyl 1-indolinecarboxylate
• CAS NO: 61589-17-1
• Molecular Formula: C₁₁H₁₃NO₂
• Molecular Weight: 191.22642
• Mol File: 61589-17-1.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ethyl 1-indolinecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 1-indolinecarboxylate(61589-17-1)
• EPA Substance Registry System: ethyl 1-indolinecarboxylate(61589-17-1)

Safety Data

• Hazardous Substances Data: 61589-17-1(Hazardous Substances Data)

Upstream product

• 496-15-1 1-indoline 
• 124-38-9 carbon dioxide 
• 75-03-6 ethyl iodide 
• 541-41-3 chloroformic acid ethyl ester 

Downstream Products

• 496-15-1 1-indoline 
• 28131-24-0 tert-butyl N-methyl-N-(phenyl)carbamate 
• 16078-34-5 5-Acetyl-2,3-dihydro-1H-indole 

Relevant articles and documents

Cp*CoIII-Catalyzed C(7)–H Bond Annulation of Indolines with Alkynes

An efficient protocol for the synthesis of biologically essential pyrroloquinolinones has been developed under Cp*CoIII catalysis, which involves a cascade reaction of C(7)-H alkenylation with alkynes followed by nucleophilic addition. A wide variety of internal alkynes including enyne, diyne, and ynamide and more challenging terminal alkynes were successfully employed for the annulation in good to excellent yield with high regioselectivity.

Palladium-catalyzed intramolecular reductive cross-coupling of Csp 2-Csp3 bond formation

A Pd-catalyzed efficient reductive cross-coupling reaction without metallic reductant to construct a Csp2-Csp3 bond has been reported. A PdIV complex was proposed to be a key intermediate, which subsequently went through d

ALLOSTERIC BINDING COMPOUNDS

The present invention relates to allosteric binding compounds of formula (I), especially for the treatment of CNS disorders, together with pharmaceutical compositions and methods of treatment including these compounds.