616-84-2

Usage

Uses

Used in Dye and Pigment Production:
2-Nitroaniline-4-sulfonic acid is utilized as a key intermediate in the synthesis of dyes and pigments, contributing to the coloration of various materials due to its chemical structure and properties.
Used in Chemical Processes:
In the realm of chemical processes, 2-Nitroaniline-4-sulfonic acid serves as a reagent, facilitating specific reactions and transformations that are essential for the production of a range of chemical products.
Used in Pharmaceutical Synthesis:
2-Nitroaniline-4-sulfonic acid is employed as a precursor in the synthesis of pharmaceuticals, playing a crucial role in the development of new drugs and medicinal compounds.
Used in Organic Compound Synthesis:
As a precursor, 2-Nitroaniline-4-sulfonic acid is also instrumental in the synthesis of other organic compounds, broadening its applications across different sectors of the chemical industry.

InChI:InChI=1/C6H6N2O5S/c7-5-2-1-4(14(11,12)13)3-6(5)8(9)10/h1-3H,7H2,(H,11,12,13)/p-1

Upstream product

• 584-49-6 4-bromo-3-nitro-benzenesulfonic acid 
• 88-74-4 2-nitro-aniline 
• 103-84-4 Acetanilid 
• 121-18-6 3-nitro-4-chlorobenzenesulfonic acid 
• 109885-37-2 disodium salt of N-nitrosulfanilic acid 
• 7664-93-9 sulfuric acid 
• 7553-56-2 iodine 
• 7697-37-2 nitric acid 
• 121-57-3 4-aminobenzene sulfonic acid 
• 159194-76-0 4-acetylamino-3-nitro-benzenesulfonic acid 

Downstream Products

• 14938-85-3 4-Hydrazino-3-nitro-benzolsulfonsaeure 
• 616-85-3 4-hydroxy-3-nitrobenzene sulfonic acid 
• 827-23-6 2,4-dibromo-6-nitroaniline 
• 84202-56-2 4-amino-3-nitrobenzenesulfonyl chloride 
• 7474-78-4 orthaminic acid 
• 1025698-05-8 2,2'-dinitro-azobenzene-4,4'-disulfonic acid 
• 139360-58-0 2-nitro-4-sulfo-benzenediazonium-betaine 
• 88-74-4 2-nitro-aniline 
• 20020-15-9 2,4,N-trinitro-aniline 
• 7664-41-7 ammonia 
• 634-89-9 1,2,3,5-tetrabromobenzene 

Relevant academic research and scientific papers

Synthesis and antistaphylococcal activity of N-substituted-1H- benzimidazole-sulphonamides

A series of N-substituted-1H-benzimidazole-5(6)-sulfonamides and 3-(5,6-dichloro-1H-benzimidazol-2-yl)-N-substituted benzensulfonamides were synthesized and evaluated for antibacterial activity against Staphylococcus aureus and methicillin-resistant S. aureus (MRSA). Certain compounds inhibit bacterial growth with low MIC (μg/mL) values. The most active compounds 30, 31, and 32 have the lowest MIC values with 0.39 to 0.19 μg/mL. Among the compounds having sulfonamido moities, 16, 23, and 24 exhibited the strongest antibacterial activity with 1.56 μg/mL MIC values.

Bisazo brown reactive dye

A brown reactive dye represented by a free acid of the formula, STR1 wherein R is a hydrogen atom or a C1 to C4 alkyl group, X is --SO2 CH2 CH2 Cl, --SO2 CH=CH2, --SO2 CH2 CH2 OSO3 H or --SO2 CH2 CH2 OPO3 H2, rings A, B and C are each a benzene or naphthalene ring which may have other substituent, m is 0 to 3 and n is 0 to 1. This dye is suitable for dyeing cellulose fibers brown to afford dyeings superior in fastnesses, acid stability, build-up property and level dyeing property.

N-NITRATION OF PRIMARY AROMATIC AMINES BY POLYNITRO AND POLYNITROXY COMPOUNDS

The possibility of N-nitration of primary aromatic amines containing SO3H and COOH groups by polynitro compounds C(NO2)4, (O2N)3CC(NO2)3, CH3C(NO2)3, C(NO2)3CH2CH2CN, and C(NO2)3CH2CH2COOCH3 and by polynitroxy compounds C(CH2ONO2)4 and HOCH2C(CH2ONO2)3 was investigated.In the presence of alkaline agents tetranitromethane, hexanitroethane, and pentaerythritol tetranitrate nitrate para- and meta-substituted aromatic amines with the formation of the corresponding nitroamine salts.Ortho-substituted amines do not enter into this reaction.

Process for the production of 2-aryl-2H-benzotriazoles

A process for the production of 2-aryl-2H-benzotriazoles comprises reducing and cyclizing the corresponding o-nitroazobenzenes with hydrogen at a temperature in the range of about 20° C. to about 100° C. and at a pressure in the range of about 15 psia (1 atmosphere) to about 1000 psia (66 atmospheres) in an alkaline medium at a pH over 10 in the presence of a nickel catalyst, preferably molybdenum-promoted Raney nickel. High yields of pure product are obtained directly with a concomitant reduction of undesired by-product and a reduction in effluent pollution problems.

Process for the production of 2-aryl-2H-benzotriazoles

A process for the production of 2-aryl-2H-benzotriazoles comprises reducing and cyclizing the corresponding o-nitroazobenzenes with hydrogen at a temperature in the range of about 20° C. to about 100° C. and at a pressure in the range of about 15 psia (1 atmosphere) to about 1000 psia (66 atmospheres) in an organic solvent mixture containing an organic amine at a pH over 10 in the presence of noble metal hydrogenation catalyst, preferably palladium. High yields of pure product are obtained with a concomitant reduction of undesired by-products and a reduction in effluent pollution problems.

Process for the production of 2-aryl-2H-benzotriazoles

A process for the production of 2-aryl-2H-benzotriazoles comprises reducing and cyclizing the corresponding o-nitroazobenzenes with carbon monoxide at a temperature in the range of about 20° C. to about 150° C. and at a pressure in the range of about 15 psia (1 atmosphere) to about 1000 psia (66 atmospheres) in an alkaline medium at a pH over 10 in the presence of a copper-amine complex catalyst. High yields of pure product are obtained with a concomitant reduction of undesired by-products and a reduction in effluent pollution problems.

Azo dyestuffs

Azo dyestuffs, which in the acid form, are represented by the formula: wherein A is an aromatic radical, M is a 1,4-benzene radical which may be substituted, E is the residue of a coupling component which is free from azo groups, At least one of A and M containing a phosphonic acid group, and the metal complexes of those having a metallisable group are reactive dyes suitable for use in the process of German OLS No. 2324809.

Process for the production of 2-aryl-2H-benzotriazoles

An improved process for the production of 2-aryl-2H-benzotriazoles by the reduction of o-nitroazobenzene intermediates with zinc in alkaline medium comprises employing a ratio of moles of alkali to moles of o-nitroazobenzene intermediate in the range of 0.2-1.7/1 in the presence of less than 150 ppm of iron based on zinc used. The improved process results in higher yields of high purity products with a concomitant reduction in the amount of undesired cleavage amine by-products and a reduction in effluent pollution problems. The process is carried out in a polar/non-polar solvent mixture.