61658-41-1

Basic information

• Product Name: furomollugin
• Synonyms: furomollugin;5-Hydroxynaphtho[1,2-b]furan-4-carboxylic acid methyl ester
• CAS NO: 61658-41-1
• Molecular Formula: C14H10O4
• Molecular Weight: 242.23
• Mol File: 61658-41-1.mol
• Article Data: 7

Chemical Properties

• Melting Point: 42 °C
• Boiling Point: 391.6±22.0 °C(Predicted)
• Appearance: /
• Density: 1.370±0.06 g/cm3(Predicted)
• PKA: 8.89±0.30(Predicted)
• CAS DataBase Reference: furomollugin(CAS DataBase Reference)
• NIST Chemistry Reference: furomollugin(61658-41-1)
• EPA Substance Registry System: furomollugin(61658-41-1)

Safety Data

• Hazardous Substances Data: 61658-41-1(Hazardous Substances Data)

Usage

General Description

Furomollugin is a natural chemical compound found in the roots of the medicinal plant Rubia cordifolia. It is known for its anti-inflammatory, antioxidant, and anticancer properties. Furomollugin has been studied for its potential therapeutic effects in treating various medical conditions, such as arthritis, cancer, and inflammatory disorders. It is believed to work by reducing inflammation, scavenging free radicals, and inhibiting the growth of cancer cells. Furomollugin shows promise as a potential candidate for the development of new drugs for the treatment of various diseases. Further research is needed to fully understand its mechanism of action and potential clinical applications.

Upstream product

• 77060-74-3 methyl 1,4-dihydroxy-2-naphthoate 
• 31519-22-9 1,4-dihydroxy-2-naphthoic acid 
• 1452153-38-6 methyl 2-butoxy-5-hydroxy-2,3-dihydronaphtho[1,2-b]furan-4-carboxylate 
• 105379-29-1 methyl 1-hydroxy-4-methoxy-2-naphthoate 
• 111-34-2 -butyl vinyl ether 
• 83575-14-8 2-methoxycarbonyl-1,4-naphthoquinone 
• 1452153-60-4 methyl 2-ethoxy-5-hydroxy-2,3-dihydronaphtho[1,2-b]furan-4-carboxylate 
• 1218784-18-9 methyl 3,6-dihydroxy-2,2-dimethyl-3,4-dihydro-2H-benzo-[h]chromene-5-carboxylate 
• 1042102-99-7 oxomollugin 
• 849591-16-8 1,4-dihydroxy-3-((E)-3-hydroxy-3-methyl-but-1-enyl)-naphthalene-2-carboxylic acid methyl ester 
• 849591-13-5 3-((E)-3-hydroxy-3-methyl-but-1-enyl)-1,4-dioxo-1,4-dihydro-naphthalene-2-carboxylic acid methyl ester 

Relevant articles and documents

A four-step total synthesis of radermachol

Radermachol has been synthesized in four steps and an overall yield of 22% via key ytterbium triflate catalyzed furannulation and intramolecular nucleophilic acylation reactions.

ortho-quinone methides from para-quinones: Total synthesis of rubioncolin B

A concise synthesis of rubioncolin B is described, which features an unprecedented intramolecular Diels-Alder reaction involving an ortho-quinone methide and a naphthofuran moiety. The ortho-quinone methide is generated through a surprisingly facile tautomerization of a para-quinone. Copyright

A novel and efficient synthesis of diverse dihydronaphtho[1,2-b]furans using the ceric ammonium nitrate-catalyzed formal [3 + 2] cycloaddition of 1,4-naphthoquinones to olefins and its application to furomollugin

A novel approach was developed for the synthesis of diverse dihydronaphtho[1,2-b]furans from 1,4-naphthoquinones and olefins in the presence of ceric ammonium nitrate. This reaction provides a rapid route for the synthesis of a variety of dihydronaphtho[1,2-b]furans and naphtho[1,2-b]furans bearing different substituents. This methodology was also used to synthesize the biologically important natural product furomollugin in only 2 steps. The Royal Society of Chemistry.