616890-44-9

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 908598-98-1 (R)-2-Dibenzylamino-butane-1,4-diol 
• 100-39-0 benzyl bromide 

Downstream Products

• 1397262-11-1 (3R)-4-{[tert-butyl(diphenyl)silyl]oxy}-3-(dibenzylamino)butan-1-ol 
• 1397262-13-3 O-phenyl [(2R)-1-{[tert-butyl(diphenyl)silyl]oxy}-4-hydroxybutan-2-yl]carbamothioate 
• 1187575-49-0 N-[(2R)-1-{[tert-butyl(diphenyl)silyl]oxy}-4-hydroxybutan-2-yl]hydrazinecarbothioamide 
• 1397262-10-0 (6R)-N,N-dibenzyl-2,2,10,10,11,11-hexamethyl-3,3-diphenyl-4,9-dioxa-3,10-disiladodecan-6-amine 
• 1585999-77-4 (3R,4S)-3-(benzylamino)-4-(methoxymethoxy)hept-6-en-1-ol 
• 1585999-62-7 (3R,4S)-N,N-dibenzyl-1-(tert-butyldimethylsilyloxy)-4-(methoxymethoxy)hept-6-en-3-amine 
• 1585999-61-6 (4S,5R)-7-(tert-butyldimethylsilyloxy)-5-(dibenzylamino)hept-1-en-4-ol 
• 1585999-64-9 C₂₉H₄₇NO₅Si 
• 1585999-63-8 C₂₉H₄₇NO₅Si 
• 1585999-80-9 2-[(2R,3S)-1-benzyl-3-(methoxymethoxy)-2,3,4,7-tetrahydro-1H-azepin-2-yl]ethanol 
• 1585999-79-6 (3R,4S)-3-[allyl(benzyl)amino]-4-(methoxymethoxy)hept-6-en-1-ol 
• 1585999-78-5 C₂₂H₃₉NO₃Si 
• 616890-48-3 benzyl (2E,4S,5R)-5-(dibenzylamino)-7-(tert-butyldimethylsilyloxy)-4-(methoxymethoxy)hept-2-enoate 
• 616890-47-2 (3R,4R)-4-(dibenzylamino)-6-(tert-butyldimethylsilyloxy)-3-(methoxymethoxy)hexane-1,2-diol 

Relevant academic research and scientific papers

Exploration of a new type of antimalarial compounds based on febrifugine

Febrifugine (1), a quinazoline alkaloid, isolated from Dichroa febrifuga roots, shows powerful antimalarial activity against Plasmodium falciparum. The use of 1 as an antimalarial drug has been precluded because of side effects, such as diarrhea, vomiting