61692-98-6

Upstream product

• 124-41-4 sodium methylate 
• 143959-07-3 ethyl N-nitroso-N-<(E)-2-phenyl-3-cyclopropyl>carbamate 
• 1009080-87-8 C₂₁H₂₀F₃NO 
• 1009080-81-2 C₂₁H₂₀F₃NO 
• 1149-56-0 (E)-4-trifluoromethylstilbene 
• 455-19-6 4-Trifluoromethylbenzaldehyde 
• 1100-88-5 benzyltriphenylphosphonium chloride 
• 100-52-7 benzaldehyde 
• 1666-17-7 benzaldehyde p-toluenesulfonylhydrazone 
• 705-31-7 4-trifluoromethylphenylacetylene 
• 402-49-3 4-bromomethyltrifluoromethylbenzene 
• 143958-98-9 ethyl N-<(E)-2-phenyl-3-<(p-trifluoromethyl)phenyl>cyclopropyl>carbamate 
• 24601-57-8 (E)-2-phenyl-3-cyclopropanecarboxylic acid 
• 61692-88-4 1-(3-phenylprop-2-yn-1-yl)-4-(trifluoromethyl)benzene 

Downstream Products

• 1173936-92-9 (E)-1-(2-(methylthio)phenyl)-2-phenyl-4-(4-(trifluoromethyl)phenyl)but-3-en-1-one 
• 1173936-91-8 (E)-1-(2-(methylthio)phenyl)-4-phenyl-2-(4-(trifluoromethyl)phenyl)but-3-en-1-one 

Relevant academic research and scientific papers

CuI-catalyzed cross-coupling of N-tosylhydrazones with terminal alkynes: Synthesis of 1,3-disubstituted allenes

A CuI-catalyzed synthesis of 1,3-disubstituted allenes from 1-alkynes by the reaction with various N-tosylhydrazones has been developed. This method, which uses readily available starting materials and is operationally simple, offers 1,3-disubstituted all

Gold-catalyzed highly enantioselective synthesis of axially chiral allenes

Axially chiral allenes are synthesized from chiral propargylamines catalyzed by KAuCl4 in high yields (up to 93% yield) and excellent enantioselectivities (up to 97% ee) in CH3CN at 40 °C. The reaction has been applied to the synthes

Electron Demand in the Transition State of the Cyclopropylidene to Allene Ring Opening

The electronic structure of the transition state for the cyclopropylidene to allene conversion has been probed.The methodology involved the relative rates of ring opening vs trapping by MeOH for a series of variously substituted 2,3-diarylcyclopropylidenes.With the assumption that the rate of trapping was unaffected by substituents, a Hammett correlation was constructed.The negative value (-0.72) for ρ indicated that the carbenic center attracts electron density in the ring-opening transition state, much like the cyclopropyl cation to allyl cation transition state.Temperature-dependent studies showed that the observed preference for ring opening was driven by entropy factors.Also, using reasonable estimates for the close to diffusion-controlled trapping activation enthalpies, the derived enthalpies for ring opening were in close agreement with the best theoretical values.