6170-27-0Relevant academic research and scientific papers
Simple preparation process of syn phenylpropanolamines from racemic O-TBDPS cyanohydrins
Li, Qing-Lan,Tang, Shi,Zhou, Dong,Tang, Xin-Mei
supporting information, p. 1600 - 1607 (2014/06/09)
In this article, a practically interesting route for the diastereoselective synthesis of phenylpropanolamines has been demonstrated for the first time. Using racemic O-tert-butyldiphenylsilyl (TBDPS) cyanohydrins as the starting materials, various syn phenylpropanolamines and derivatives (e.g., norpseudophedrine) have been successfully prepared in exellent diastereoselectivity via a practically interesting process.
NON-CATALYTIC REDUCTION OF Α-OXIMINOKETONES AND Α-OXIMINOALCOHOLS TO ERYTHRO-2-AMINO-1-ARYLALKAN-1-OLS
Oppong-Boachie, Francis Kwabena
, p. 293 - 298 (2007/10/02)
A non-catalytic reduction of α-oximinoketones 1 and α-oximinoalcohols 2 to erythro-2-amino-1-arylalkan-1-ols 3 with lithium aluminium hydride is reported.The erythro-2-amino-1-arylalkan-1-ols are isolated as their hydrochlorides 5 and characterised as the erythro isomers by benzoylation.
