65737-01-1

Upstream product

• 65737-01-1 erythro-2-benzamido-1-phenylbutan-1-ol 
• 25994-02-9 2-Hydroxyimino-1-phenyl-1-butanone 
• 6170-27-0 (+/-)-(1R,2S)-2-amino-1-phenyl-1-butanol hydrochloride 
• 98-88-4 benzoyl chloride 

Downstream Products

• 65737-05-5 1-phenyl-3-ethylisoquinoline 
• 65737-01-1 threo-2-benzamido-1-phenylbutan-1-ol 
• 82894-63-1 4-ethyl-1-phenylisoquinoline 
• 65737-02-2 trans-2,5-diphenyl-4-ethyl-Δ²-oxazoline 
• 66166-31-2 2,5-diphenyl-4-ethyl-Δ²-oxazoline 

Relevant academic research and scientific papers

NON-CATALYTIC REDUCTION OF Α-OXIMINOKETONES AND Α-OXIMINOALCOHOLS TO ERYTHRO-2-AMINO-1-ARYLALKAN-1-OLS

A non-catalytic reduction of α-oximinoketones 1 and α-oximinoalcohols 2 to erythro-2-amino-1-arylalkan-1-ols 3 with lithium aluminium hydride is reported.The erythro-2-amino-1-arylalkan-1-ols are isolated as their hydrochlorides 5 and characterised as the erythro isomers by benzoylation.

ISOQUINOLINE SYNTHESES VI-A Δ2-OXAZOLINES. PART II. SYNTHESES OF 1-PHENYL-3-ALKYLISOQUINOLINES BY PICTET-GAMS REACTION

The conditions necessary for transformation of hydroxyamides (1), Δ2-oxazolines (7) and chloroamides (6) into 1-phenyl-3-alkylisoquinolines have been established.A mechanism of the Pictet-Gams reaction has been proposed claiming the existence o