618068-86-3Relevant articles and documents
1-[2-(2-Hydroxyalkyl)phenyl]ethanone: A New Photoremovable Protecting Group for Carboxylic Acids
Atemnkeng, Walters N.,Louisiana II, Larry D.,Yong, Promise K.,Vottero, Breanne,Banerjee, Anamitro
, p. 4469 - 4471 (2007/10/03)
(Equation presented) A new photoremovable protecting group for carboxylic acids is introduced. The protecting group 1-[2-(2-hydroxyalkyl)phenyl]ethanone, HAPE, is used to protect various carboxylic acids. When photolyzed, the protected compound releases the acid in 70-85% isolated yields. The synthesis and the results of photorelease of the protected acids are presented here.