618120-15-3

Upstream product

• 593251-63-9 (E)-5-(2-hydroxy-6-methoxyphenyl)-3-methylpent-2-enyl methyl carbonate 
• 593251-76-4 Carbonic acid (Z)-5-(2-hydroxy-6-methoxy-4-methyl-phenyl)-3-methyl-pent-2-enyl ester methyl ester 
• 593251-70-8 (R)-5-methoxy-2,7-dimethyl-2-vinylchroman 
• 593251-60-6 (R)-5-methoxy-2,7-dimethylchroman-2-carboxyaldehyde 
• 502763-34-0 (S)-1-[1′-benzenesulfonyl]methyl-2,2-dimehtyl-6-methylenecyclohexane 
• 502763-33-9 (S)-(-)-2,2-dimethyl-6-methylene-1-[1'-(phenylthio)methyl]cyclohexane 
• 166022-29-3 (S)-(+)-(2',2'-dimethyl-6'-methylene-1'-cyclohexyl)methanol 

Downstream Products

• 782474-51-5 Toluene-4-sulfonic acid (1S,2S)-1-hydroxy-2-[2-((S)-5-methoxy-2,7-dimethyl-2H-chromen-2-yl)-ethyl]-3,3-dimethyl-cyclohexylmethyl ester 
• 618120-18-6 (1S,2S)-1-hydroxymethyl-2-[(2S)-2-(5-methoxy-2,7-dimethyl-2H-chromen-2-yl)ethyl]-3,3-dimethylcyclohexanol 
• 22733-60-4 siccanin 

Relevant academic research and scientific papers

Biomimetic enantioselective total synthesis of (-)-siccanin via the Pd-catalyzed asymmetric allylic alkylation (AAA) and sequential radical cyclizations

(-)-Siccanin (1), a natural product possessing significant antifungal properties, was synthesized enantioselectively via a biomimetic route. This synthetic route features two sequential radical cyclizations: a Ti(III)-mediated radical cyclization of epoxy

An enantioselective biomimetic total synthesis of (-)-siccanin

A convergent asymmetric synthesis of the clinically important antifungal agent (-)-siccanin (1) mimics the proposed biosynthetic pathway. A Pd-catalyzed asymmetric allylic alkylation was used to establish the stereochemistry, and sequential radical proces