61878-31-7

Upstream product

• 27167-65-3 (S)-tert-butyl 2-((S)-2-(((benzyloxy)carbonyl)amino)propanamido)-4-methylpentanoate 
• 81578-33-8 (S)-4-Methyl-2-[(S)-2-(1,1,3-trioxo-1λ⁶,3λ⁴-[1,3]dithian-2-ylmethoxycarbonylamino)-propionylamino]-pentanoic acid tert-butyl ester 
• 124-40-3 dimethyl amine 
• 82325-98-2 (S)-4-Methyl-2-[(S)-2-(1,1,3,3-tetraoxo-1λ⁶,3λ⁶-[1,3]dithian-2-ylmethoxycarbonylamino)-propionylamino]-pentanoic acid tert-butyl ester 
• 81578-17-8 Dmoc-Ala-Leu-OtBu 
• 82325-98-2 4-Methyl-2-[2-(1,1,3,3-tetraoxo-1λ⁶,3λ⁶-[1,3]dithian-2-ylmethoxycarbonylamino)-propionylamino]-pentanoic acid tert-butyl ester 
• 182485-42-3 (S)-4-Methyl-2-[(S)-2-(4-phenylacetoxy-benzyloxycarbonylamino)-propionylamino]-pentanoic acid tert-butyl ester 
• 21691-53-2 L-leucine tert-butyl ester 

Downstream Products

• 81578-37-2 1,3-Dithian-2-ylmethoxycarbonyl-L-phenylalanyl-L-leucyl-L-alanyl-L-leucin-tert-butylester 
• 75305-96-3 N-2-Phenyl-iso-propyloxycarbonyl-S-ethylthio-cysteinyl-alanyl-leucin-tert.-butylester 
• 22849-49-6 H-Gly-L-Ala-L-Leu-OH 

Relevant academic research and scientific papers

METHOD FOR PRODUCING AMIDE COMPOUND

Provided is a novel method for producing amide compounds at high stereochemical selectivities. The method according to the present invention for producing amide compounds is provided with an amidation step for reacting, in the presence of a catalyst compr

Stereocontrolled [11C]Alkylation of N-Terminal Glycine Schiff Bases To Obtain Dipeptides

The use of various quaternary ammonium salts as chiral phase-transfer catalysts allowed effective and stereoselective radiochemical [11C]alkylation to obtain functionalized dipeptides. We herein report a broadly applicable procedure for the asymmetric [11C]alkylation of dipeptides to give labeled N-terminal peptides by using different [11C]alkyl halides. Contended stereoselectivities of the reactions were observed by using 11C-labeled alkyl halides, [11C]methyl iodide and [11C]benzyl iodide, and diastereomeric ratios with different specialized catalysts of 95:5 and 90:10 were achieved, respectively. Accordingly, the straightforward synthesis of enantioenriched compounds should play a vital role in peptide-based radiopharmaceutical development and positron emission tomography imaging.

Chemoenzymatic synthesis of a characteristic phosphorylated and glycosylated peptide fragment of the large subunit of mammalian RNA polymerase II

The covalent modification of proteins by phosphorylation and addition of GlcNAc residues are important regulatory processes which mediate biological signal transduction. For instance, the cytosolic form of RNA polymerase II is heavily glycosylated but dur

Enzymatische Synthese eines charakteristischen phosphorylierten und glycosylierten Peptidfragmentes der grossen Untereinheit der RNA-Polymerase II aus Saeugetieren

Keywords: Enzyme; Glycopeptide; Peptide; Schutzgruppen

The 1,3-Dithian-2-ylmethoxycarbonyl (Dmoc) Group as Two-Step Amino Protective Function in Peptide Chemistry

The 1,3-dithian-2-ylmethoxycarbonyl (Dmoc) group (4) as amino protective function is stable against bases and trifluoroacetic acid.The peptide condensation of Dmoc-amino acids is carried out applying the mixed anhydride or modified carbodiimide procedures

Selectively S-Protected Cysteine Peptides. IV. Synthesis of Cysteine Peptides Using the S-Ethylthio Protecting Group. II

Studying the problems of the selective sulphur protection in cysteine peptides, a model octapeptide from the sheep insulin A-chain was prepared by conventional synthesis using the S-ethylthio and the S-diphenylmethyl group.As consequence of the small acid

Amino Acids and Peptides. XXX. Phosphorus in Organic Synthesis. XVII. Application of Diphenyl Phosphorazidate (DPPA) and Diethyl Phosphorocyanidate (DEPC) to Solid-phase Peptide Synthesis

Two coupling reagents for peptide synthesis, diphenyl phosphorazidate (DPPA) and diethyl phosphorocyanidate (DEPC), were tested using the solid-phase method.The reactivities of DPPA and DEPC were examined by coupling Boc-Ile with Gly-resin.In a comparison