61954-82-3

Basic information

• Product Name: 5-BroMo-4-phenylthiazol-2-aMine
• Synonyms: 5-BroMo-4-phenylthiazol-2-aMine;5-bromo-4-phenyl-2-Thiazolamine
• CAS NO: 61954-82-3
• Molecular Formula: C₉H₇BrN₂S
• Molecular Weight: 255.13428
• Mol File: 61954-82-3.mol
• Article Data: 15

Chemical Properties

• Melting Point: 107-108 °C
• Boiling Point: 395.113°C at 760 mmHg
• Flash Point: 192.757°C
• Appearance: /
• Density: 1.637g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.685
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 2.61±0.10(Predicted)
• CAS DataBase Reference: 5-BroMo-4-phenylthiazol-2-aMine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BroMo-4-phenylthiazol-2-aMine(61954-82-3)
• EPA Substance Registry System: 5-BroMo-4-phenylthiazol-2-aMine(61954-82-3)

Safety Data

• Hazardous Substances Data: 61954-82-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H7BrN2S/c10-8-7(12-9(11)13-8)6-4-2-1-3-5-6/h1-5H,(H2,11,12)

Upstream product

• 70-11-1 α-bromoacetophenone 
• 98-86-2 acetophenone 
• 17356-08-0 thiourea 
• 5039-09-8 2-acetamide-4-phenyl-1,3-thiazole 
• 113511-22-1 5-bromo-4-phenyl-thiazol-2-ylamine; hydrobromide 
• 2010-06-2 2-Amino-4-phenylthiazole 

Downstream Products

• 185335-68-6 1-(5'-bromo-4'-phenylthiazolyl)-3-(2-chloroethyl)urea 
• 1391980-01-0 4-phenyl-5-{[4-(trifluoromethyl)phenyl]oxy}-1,3-thiazol-2-amine 
• 1391980-00-9 4-phenyl-5-{[2-(trifluoromethyl)phenyl]oxy}-1,3-thiazol-2-amine 
• 6318-74-7 2-amino-4,5-diphenylthiazole 
• 1391979-65-9 2-[4-(ethylsulfonyl)phenyl]-N-(5-{[4-(methyloxy)phenyl]oxy}-4-phenyl-1,3-thiazol-2-yl)acetamide 
• 1391979-63-7 2-[4-(ethylsulfonyl)phenyl]-N-(4-phenyl-5-{[4-(trifluoromethyl)phenyl]oxy}-1,3-thiazol-2-yl)acetamide 
• 1391979-61-5 N-{5-[(4-chlorophenyl)oxy]-4-phenyl-1,3-thiazol-2-yl}-2-[4-(ethylsulfonyl)phenyl]acetamide 
• 1391979-59-1 2-[4-(ethylsulfonyl)phenyl]-N-(4-phenyl-5-{[2-(trifluoromethyl)phenyl]oxy}-1,3-thiazol-2-yl)acetamide 
• 1391979-57-9 N-{5-[(2-chlorophenyl)oxy]-4-phenyl-1,3-thiazol-2-yl}-2-[4-(ethylsulfonyl)phenyl]acetamide 
• 1391979-55-7 2-[4-(ethylsulfonyl)phenyl]-N-[4-phenyl-5-(phenyloxy)-1,3-thiazol-2-yl]acetamide 

Relevant articles and documents

Discovery of a novel orally active TRPV4 inhibitor: Part 1. Optimization from an HTS hit

-

SUBSTITUTED PROPANAMIDES AS INHIBITORS OF NUCLEASES

The invention provides compounds represented by the structural formula (1): wherein R1, R2, R3, R4, R5, R6 are as defined in the claims. The compounds are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.

THIAZOLE MODULATORS OF A3 ADENOSINE RECEPTORS

Modulators of adenosin A3 receptors of formula (I) and procedure for preparing these compounds. Other objectives of the present invention are to provide pharmaceutical compositions comprising an effective amount of these compounds and the use o