6200-49-3Relevant articles and documents
Synthesis of thiazolidinimines/thiazinan-2-imines via three-component coupling of amines, vic-dihalides and isothiocyanates under metal-free conditions
Kumar, Rahul,Joshi, Abhisek,Rawat, Deepa,Adimurthy, Subbarayappa
supporting information, p. 1340 - 1352 (2021/02/22)
An expeditious approach for the synthesis of thiazolidin-2-imines and 1,3-thiazinan-2-imines through three-components coupling (TCC) of amines, isothiocynates and dihalides under metal-free conditions has been described. Dichloroethane (DCE) employed as two carbon (C2) source for the annulation and obtained saturated five membered heterocycles.With 1,3-dibromopropane, six membered heterocycles were obtained in good yields. The metal-free, broad substrate scope, functional group tolerance and applicability at gram scale synthesis are the advantages of the present protocol.
The Preparation of Cyclic Dithia and Thiaza Compounds by the Reaction of Potassium Carbonate with Heterocumulenes and Alkylene Dibromides or Carbonate Catalyzed by Organostannyl Compounds
Fujinami, Tatsuo,Sato, Shinichi,Uchida, Norimasa,Sakai, Shizuyoshi
, p. 1174 - 1177 (2007/10/02)
Cyclic 1,3-dithia- and 1,3-thiaza-2-ylidene compounds were obtained by the heterogenous reaction of solid potassium carbonate, a sulfur-containing heterocumulene, such as aryl isothiocyanate, carbon disulfide, or carbonyl silfide, and alkylene dibromides or ethylene carbonate in the presence of bis(tributylstannyl) compounds.The effect of an organostannyl catalyst on these reactions is discussed.