6200-49-3Relevant academic research and scientific papers
Synthesis of thiazolidinimines/thiazinan-2-imines via three-component coupling of amines, vic-dihalides and isothiocyanates under metal-free conditions
Kumar, Rahul,Joshi, Abhisek,Rawat, Deepa,Adimurthy, Subbarayappa
supporting information, p. 1340 - 1352 (2021/02/22)
An expeditious approach for the synthesis of thiazolidin-2-imines and 1,3-thiazinan-2-imines through three-components coupling (TCC) of amines, isothiocynates and dihalides under metal-free conditions has been described. Dichloroethane (DCE) employed as two carbon (C2) source for the annulation and obtained saturated five membered heterocycles.With 1,3-dibromopropane, six membered heterocycles were obtained in good yields. The metal-free, broad substrate scope, functional group tolerance and applicability at gram scale synthesis are the advantages of the present protocol.
Regioselective Cycloaddition of 1,2-Disubstituted Aziridines to Heterocumulenes Catalyzed by Organoantimony Halides
Nomura, Ryoki,Nakano, Takahiro,Nishio, Yoshitaka,Ogawa, Sachiko,Ninagawa, Akira,Matsuda, Haruo
, p. 2407 - 2410 (2007/10/02)
In the presence of catalytic amounts of organoantimony(V) halides such as Ph4SbI, Ph4SbBr, Ph3SbBr2, and Ph3SbCl2, the cycloaddition of aziridines 1a-g with heterocumulenes (phenyl isothiocyanate, carbon disulfide, and carbon dioxide) selectively gave ring-expanded cycloadducts 3a-d, f, g and 6e by α-cleavage of the aziridine rings. - Key Words: Organoantimony halides / Aziridines, cycloaddition of, α-cleavage of / Heterocumulenes
The Preparation of Cyclic Dithia and Thiaza Compounds by the Reaction of Potassium Carbonate with Heterocumulenes and Alkylene Dibromides or Carbonate Catalyzed by Organostannyl Compounds
Fujinami, Tatsuo,Sato, Shinichi,Uchida, Norimasa,Sakai, Shizuyoshi
, p. 1174 - 1177 (2007/10/02)
Cyclic 1,3-dithia- and 1,3-thiaza-2-ylidene compounds were obtained by the heterogenous reaction of solid potassium carbonate, a sulfur-containing heterocumulene, such as aryl isothiocyanate, carbon disulfide, or carbonyl silfide, and alkylene dibromides or ethylene carbonate in the presence of bis(tributylstannyl) compounds.The effect of an organostannyl catalyst on these reactions is discussed.
