6216-67-7

Upstream product

• 1054645-97-4 Phenoxy-acetic acid (2R,3R,4R,5R)-5-[((S)-2-benzyloxycarbonylamino-4-methyl-pentyloxy)-hydroxy-phosphoryloxymethyl]-4-(2-phenoxy-acetoxy)-2-[6-(2-phenoxy-acetylamino)-purin-9-yl]-tetrahydro-furan-3-yl ester 
• 57018-82-3 5'-O-dimethoxytrityladenosine 
• 6216-61-1 (S)-(-)-N-(benzyloxycarbonyl)leucinol 
• 501-53-1 benzyl chloroformate 
• 24123-12-4 1-(benzyloxycarbonyl)-3-methylimidazolium chloride 
• 219677-68-6 6-N,2'-O,3'-O-tri(phenoxyacetyl)adenosine 
• 58-61-7 adenosine 
• 219677-67-5 5'-O-dimethoxytrityl-2'-O,3'-O,6-N-triphenoxyacetyladenosine 

Relevant academic research and scientific papers

Synthesis of peptidinol adenylates

Peptidinol adenylates were assembled by condensing the carboxyl group of N-blocked peptides with the alkylamino group of leucinol 5' adenosine phosphodiester. The latter was prepared as protected precursor from adenosine and leucinol by phosphite chemistry. The title compounds, which mimic aminoacyl adenylates, are designed to penetrate microorganisms via peptide permeases and to interfere with genetic translation.