62205-57-6

Upstream product

• 10378-06-0 2-methyl-(3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyranoso)[1,2-d]-2-oxazoline 
• 3068-34-6 Acetic acid (2R,3S,4R,5R,6R)-3-acetoxy-2-acetoxymethyl-5-acetylamino-6-chloro-tetrahydro-pyran-4-yl ester 
• 3006-60-8 Acetic acid (2R,3R,4R,5S,6R)-2,5-diacetoxy-6-acetoxymethyl-3-acetylamino-tetrahydro-pyran-4-yl ester 
• 17996-12-2 N-benzyloxycarbonyl-6-amino-1-hexanol 
• 62205-56-5 6-(N-benzyloxycarbonylamino)hexyl-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy)-β-D-glucopyranoside 

Downstream Products

• 74653-34-2 [6-((2R,3R,4R,5S,6R)-3-Acetylamino-4,5-bis-benzyloxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-hexyl]-carbamic acid benzyl ester 
• 74653-33-1 6-<(Benzyloxycarbonyl)amino>hexyl 2-acetamido-3,6-di-O-benzyl-2-deoxy-β-D-glucopyranoside 
• 74653-35-3 6-<(Benzyloxycarbonyl)amino>hexyl 2-acetamido-3,4,6-tri-O-benzyl-2-deoxy-β-D-glucopyranoside 
• 85472-19-1 6-[N-(benzyloxycarbonylamino)hexyl]-2-acetamido-4,6-di-O-benzylidene-2-deoxy-β-D-glucopyranoside 
• 74653-29-5 6-(benzyloxycarbonylamino)-1-hexyl 2-acetamido-2-deoxy-4,6-O-isopropylidene-β-D-glucopyranoside 
• 184293-97-8 [6-((2R,3R,4R,5S,6R)-3-Acetylamino-6-benzyloxymethyl-4,5-dihydroxy-tetrahydro-pyran-2-yloxy)-hexyl]-carbamic acid benzyl ester 
• 852311-80-9 6-[N-(benzyloxycarbonylamino)hexyl]-2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-(3,4-O-isopropylidene-α-L-fucopyranosyl)-β-D-glucopyranoside 
• 852311-79-6 6-[N-(benzyloxycarbonylamino)hexyl]-2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-(2-O-tert-butyldimethylsilyl-3,4-O-isopropylidene-α-L-fucopyranosyl)-β-D-glucopyranoside 
• 852311-82-1 6-[N-(benzyloxycarbonylamino)hexyl]-2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-[3,4-O-isopropylidene-2-O-(3,4-O-isopropylidene-α-L-fucopyranosyl)-α-L-fucopyranosyl]-β-D-glucopyranoside 
• 852311-81-0 6-[N-(benzyloxycarbonylamino)hexyl]-2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-[3,4-O-isopropylidene-2-O-(2-O-tert-butyldimethylsilyl-3,4-O-isopropylidene-α-L-fucopyranosyl)-α-L-fucopyranosyl]-β-D-glucopyranoside 
• 295349-02-9 Fmoc-Asp(CONH-[CH₂]6-O-GlcNac)-Gly-Ser-(OBn)2 
• 171612-31-0 6-(N-benzyloxycarbonylamino)hexyl-O-(2,3,4-tri-O-benzyl-α-L-fucopyranosyl)-(1->3)-2-acetamido-4,6-O-benzylidene-2-deoxy-β-D-glucopyranoside 
• 171612-32-1 6-(N-benzyloxycarbonylamino)hexyl-O-(2,3,4-tri-O-benzyl-α-L-fucopyranosyl)-(1->3)-2-acetamido-6-O-benzyl-2-deoxy-β-D-glucopyranoside 
• 171612-34-3 6-(N-benzyloxycarbonylamino)hexyl-O-(6-O-benzyl-β-D-galactopyranosyl)-(1->4)-O-[(2,3,4-tri-O-benzyl-α-L-fucopyranosyl)-(1->3)]-2-acetamido-6-O-benzyl-2-deoxy-β-D-glucopyranoside 

Relevant academic research and scientific papers

Synthesis of 2-deoxy-hexopyranosyl derivatives of uridine as donor substrate analogues for glycosyltransferases

A series of 2-deoxy-hexopyranosyl derivatives of uridine have been synthesized as analogues of UDP-sugar. These compounds were tested as inhibitors against bovine β-1,4-galactosyltransferase I in fluorescent assays and showed no significant inhibition.

Synthesis and antibody-binding studies of a series of parasite fuco-oligosaccharides

Complex multifucosylated oligosaccharides are structural elements of glycoprotein and glycolipid subsets of larval, egg, and adult stages of Schistosoma, the parasitic worms that cause schistosomiasis, a serious disease affecting more than 200 million peo

Chemo-enzymatic synthesis of glycopolymers and sequential glycopeptides bearing lactosamine and sialyl Lewisx unit pendant chains

A variety of glycoconjugates bearing either N-acetyllactosamine or sialyl Lewisx units have been synthesised in a chemo-enzymatic way. This includes the synthesis of glycopolymer copolymerised with acrylamide and whose glucosamine unit was substituted with different kinds of side-chain. Glycopeptides with different spacer-arm glucosamine units have also been prepared and polymerised. The sugar chain was then elongated using glycosyl transferases to afford the novel sequential glycopeptides. In these cases, the polymeric sugar cluster effect led to enzymatic glycosylation with high efficiency. Nevertheless, some differences have been noticed depending on the reaction conditions used for each substrate.

Large scale synthesis of linker-modified sialyl Lewis(X), Lewis(X) and N-acetyllactosamine

The synthesis of sialyl-Lewis(X) (1b), Lewis(X) (2) and N- acetyllactosamine (3), each being attached to the 1β-O-(6-amino)hexyl handle, were scaled up to gram amounts to obtain sufficient material for thorough pharmaceutical evaluations and for derivatisations aiming at more potent selectin antagonists. The disaccharide 3 was synthesised from inexpensive lactose to provide a versatile building block, either to be used for alternative approaches to the Lewis type oligosaccharides, or to prepare polyvalent LacNAc templates to be further elaborated by glycosyltransferase reactions. All syntheses were directed to reasonable large scale procedures, especially by minimising the number of steps and the use of heavy metal salts in glycosylations.

SYNTHESIS OF 6-AMINO-1-HEXYL 2-ACETAMIDO-2-DEOXY-3-, -4-, AND -6-O-β-D-GALACTOPYRANOSYL-β-D-GLUCOPYRANOSIDES

6-Aminohexyl glycosides of β-D-Gal β-D-GlcNAc disaccharides having β-(13)-, β-(14)-, and β-(16)-linkages were prepared. 6-(Benzyloxycarbonylamino)-1-hexanol was glycosylated with 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-glucopyranosyl chlor