85472-19-1

Upstream product

• 62205-57-6 6-[(N-Benzyloxycarbonyl)amino]hexyl 2-N-acetamido-2-deoxy-β-D-glucopyranoside 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 3006-60-8 Acetic acid (2R,3R,4R,5S,6R)-2,5-diacetoxy-6-acetoxymethyl-3-acetylamino-tetrahydro-pyran-4-yl ester 
• 17996-12-2 N-benzyloxycarbonyl-6-amino-1-hexanol 
• 62205-56-5 6-(N-benzyloxycarbonylamino)hexyl-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy)-β-D-glucopyranoside 
• 100-52-7 benzaldehyde 

Downstream Products

• 85472-20-4 6-(benzyloxycarbonylamino)hexyl 2-acetamido-4,6-O-benzylidene-3-O-(D-1-carboxyethyl)-2-deoxy-β-D-glucopyranoside 
• 171612-31-0 6-(N-benzyloxycarbonylamino)hexyl-O-(2,3,4-tri-O-benzyl-α-L-fucopyranosyl)-(1->3)-2-acetamido-4,6-O-benzylidene-2-deoxy-β-D-glucopyranoside 
• 852311-80-9 6-[N-(benzyloxycarbonylamino)hexyl]-2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-(3,4-O-isopropylidene-α-L-fucopyranosyl)-β-D-glucopyranoside 
• 852311-82-1 6-[N-(benzyloxycarbonylamino)hexyl]-2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-[3,4-O-isopropylidene-2-O-(3,4-O-isopropylidene-α-L-fucopyranosyl)-α-L-fucopyranosyl]-β-D-glucopyranoside 
• 852311-81-0 6-[N-(benzyloxycarbonylamino)hexyl]-2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-[3,4-O-isopropylidene-2-O-(2-O-tert-butyldimethylsilyl-3,4-O-isopropylidene-α-L-fucopyranosyl)-α-L-fucopyranosyl]-β-D-glucopyranoside 
• 85472-21-5 6-(benzyloxycarbonylamino)hexyl β-glycoside of N-acetyl-4,6-O-benzylidenemuramyl-L-alanyl-D-isoglutamine benzyl ester 
• 171612-33-2 6-(N-benzyloxycarbonylamino)hexyl-O-(2,3,4-tri-O-acetyl-6-O-benzyl-β-D-galactopyranosyl)-(1->4)-O-[(2,3,4-tri-O-benzyl-α-L-fucopyranosyl)-(1->3)]-2-acetamido-6-O-benzyl-2-deoxy-β-D-glucopyranoside 
• 171612-34-3 6-(N-benzyloxycarbonylamino)hexyl-O-(6-O-benzyl-β-D-galactopyranosyl)-(1->4)-O-[(2,3,4-tri-O-benzyl-α-L-fucopyranosyl)-(1->3)]-2-acetamido-6-O-benzyl-2-deoxy-β-D-glucopyranoside 
• 171612-32-1 6-(N-benzyloxycarbonylamino)hexyl-O-(2,3,4-tri-O-benzyl-α-L-fucopyranosyl)-(1->3)-2-acetamido-6-O-benzyl-2-deoxy-β-D-glucopyranoside 
• 852311-79-6 6-[N-(benzyloxycarbonylamino)hexyl]-2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-(2-O-tert-butyldimethylsilyl-3,4-O-isopropylidene-α-L-fucopyranosyl)-β-D-glucopyranoside 

Relevant academic research and scientific papers

Synthesis and antibody-binding studies of a series of parasite fuco-oligosaccharides

Complex multifucosylated oligosaccharides are structural elements of glycoprotein and glycolipid subsets of larval, egg, and adult stages of Schistosoma, the parasitic worms that cause schistosomiasis, a serious disease affecting more than 200 million peo

Large scale synthesis of linker-modified sialyl Lewis(X), Lewis(X) and N-acetyllactosamine

The synthesis of sialyl-Lewis(X) (1b), Lewis(X) (2) and N- acetyllactosamine (3), each being attached to the 1β-O-(6-amino)hexyl handle, were scaled up to gram amounts to obtain sufficient material for thorough pharmaceutical evaluations and for derivatisations aiming at more potent selectin antagonists. The disaccharide 3 was synthesised from inexpensive lactose to provide a versatile building block, either to be used for alternative approaches to the Lewis type oligosaccharides, or to prepare polyvalent LacNAc templates to be further elaborated by glycosyltransferase reactions. All syntheses were directed to reasonable large scale procedures, especially by minimising the number of steps and the use of heavy metal salts in glycosylations.

ω-AMINOALKYL β-GLYCOSIDES OF N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE, AND THEIR CONJUGATES WITH MENINGOCOCCAL GROUP C POLYSACCHARIDE

The 6-aminohexyl β-glycoside of N-acetylmuramyl-L-alanyl-D-isoglutamine and its spacer-arm-linked analog (3.8 nm) were synthesized from 2-methyl-(3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyrano)--2-oxazoline, and coupled with meningococcal group C polysaccharide in attempts to enhance the immunogenicity of the polysaccharide antigen.