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Trimethyl-(6-trimethylsilyloxyhexoxy)silane is a complex organic compound with the chemical formula C12H30O2Si3. It is a colorless liquid at room temperature and is soluble in common organic solvents. trimethyl-(6-trimethylsilyloxyhexoxy)silane is characterized by a central silicon atom bonded to three methyl groups and a 6-trimethylsilyloxyhexoxy group. The 6-trimethylsilyloxyhexoxy group consists of a six-carbon alkyl chain with a trimethylsilyl ether group attached to the terminal oxygen atom. This structure endows the compound with unique properties, making it useful in various applications, such as a coupling agent in organic synthesis and a reagent in the formation of silyl ethers. Its stability and reactivity are influenced by the presence of the trimethylsilyl protecting group, which can be selectively removed under certain conditions to reveal the underlying functional groups.

6222-22-6

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6222-22-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6222-22-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,2 and 2 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 6222-22:
(6*6)+(5*2)+(4*2)+(3*2)+(2*2)+(1*2)=66
66 % 10 = 6
So 6222-22-6 is a valid CAS Registry Number.
InChI:InChI=1/C12H30O2Si2/c1-15(2,3)13-11-9-7-8-10-12-14-16(4,5)6/h7-12H2,1-6H3

6222-22-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name trimethyl(6-trimethylsilyloxyhexoxy)silane

1.2 Other means of identification

Product number -
Other names TRIMETHYL-(6-TRIMETHYLSILYLOXYHEXOXY)SILANE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6222-22-6 SDS

6222-22-6Downstream Products

6222-22-6Relevant academic research and scientific papers

Fast and efficient method for Silylation of alcohols and phenols with HMDS in the presence of bis-thiourea complexes of cobalt, nickel, copper and zinc chlorides

Zeynizadeh, Behzad,Sorkhabi, Serve

, p. 127 - 135 (2018/02/06)

Bis-thiourea complexes of cobalt, nickel, copper and zinc chlorides were used efficiently for rapid and efficient trimethylsilylation of alcohols and phenols with hexamethyldisilazane (HMDS) in CH3CN. All reactions were carried out at room temperature within immediate-120?min timeframe to afford trimethylsilyl ether derivatives in high to excellent yields. Investigation of the results exhibited that the prepared bis-thiourea metal complexes show the activity as Co(tu)2Cl2> Ni(tu)2Cl2> Cu(tu)2Cl2> Zn(tu)2Cl2 in their silylation reactions.

Preparation of nano silica supported sodium hydrogen sulfate: As an efficient catalyst for the trimethyl, triethyl and t-butyldimethyl silylations of aliphatic and aromatic alcohols in solution and under solvent-free conditions

Abri, Abdolreza,Ranjdar, Somayeh

, p. 929 - 934 (2014/10/16)

Nano silica supported sodium hydrogen sulfate has been prepared by mixing NaHSO4 with activated Nano silicagel. We wish to report a new method for the synthesis of trimethyl (TMS), triethyl (TES) and t-butyldimethyl silyl (TBS) ethers from benzylic, allylic, propargylic alcohols, phenols, naphtholes and some of phenolic drugs in the solution and under solvent-free conditions.

Clean nitrations: Novel syntheses of nitramines and nitrate esters by nitrodesilylation reactions using dinitrogen pentoxide (N2O5)

Millar, Ross W.,Philbin, Simon P.

, p. 4371 - 4386 (2007/10/03)

In this novel nitration method dinitrogen pentoxide (N2O5) in an inert solvent is used as the nitrating agent, thereby removing the need for strong acids as the reaction medium. The N2O5 cleaves heteroatom-silicon bonds, in silylamines and silyl ethers respectively, to yield the desired energetic groupings (nitramines or nitrate esters respectively) without liberation of acids which would occur with conventional substrates (amines or alcohols). These nitrodesilylation reactions proceed cleanly and in good yield, and the scope of the reaction is illustrated by 29 examples, some of which produce high energy compounds, notably plasticisers and an energetic polymer precursor. These reactions are therefore potentially clean nitrations for the manufacture of energetic compounds which will minimise the impact of this activity on the environment in the future.

Carbofunctional silacyclobutanes 1. Synthesis of 1-(ω-hydroxyalkyl)silacyclobutanes

Ushakov,Fedorova

, p. 901 - 910 (2007/10/03)

A four-step synthesis of 1-(ω-hydroxyalkyl)- and 1-(4-hydroxyphenyl)silacyclobutanes was carried out. The influence of the structure of the initial compounds and the reaction conditions on the ratio of the reaction products formed was studied. The stabili

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