622373-29-9Relevant academic research and scientific papers
Identification and SAR of Glycine Benzamides as Potent Agonists for the GPR139 Receptor
Dvorak, Curt A.,Coate, Heather,Nepomuceno, Diane,Wennerholm, Michelle,Kuei, Chester,Lord, Brian,Woody, David,Bonaventure, Pascal,Liu, Changlu,Lovenberg, Timothy,Carruthers, Nicholas I.
supporting information, p. 1015 - 1018 (2015/09/22)
A focused high throughput screening for GPR139 was completed for a select 100K compounds, and new agonist leads were identified. Subsequent analysis and structure-activity relationship studies identified (S)-3-chloro-N-(2-oxo-2-((1-phenylethyl)amino)ethyl
Synthesis and separation of the enantiomers of the neuropeptide S receptor antagonist (9 R/S)-3-Oxo-1,1-diphenyl-tetrahydro-oxazolo[3,4- a ]pyrazine-7-carboxylic Acid 4-fluoro-benzylamide (SHA 68)
Trapella, Claudio,Pela, Michela,Del Zoppo, Luisa,Calo, Girolamo,Camarda, Valeria,Ruzza, Chiara,Cavazzini, Alberto,Costa, Valentina,Bertolasi, Valerio,Reinscheid, Rainer K.,Salvadori, Severo,Guerrini, Remo
, p. 2738 - 2744 (2011/06/27)
This study reports the synthesis, chromatographic separation, and pharmacological evaluation of the two enantiomers of the neuropeptide S receptor (NPSR) antagonist (9R/S)-3-oxo-1,1-diphenyl-tetrahydro-oxazolo[3,4-a]pyrazine- 7-carboxylic acid 4-fluoro-be
