622404-81-3Relevant articles and documents
Rhodium(III)-Catalyzed Sequential C?H Activation and Cyclization from N-Methoxyarylamides and 3-Diazooxindoles for the Synthesis of Isochromenoindolones
Ko, Gi Hoon,Maeng, Chanyoung,Jeong, Haneal,Han, Sang Hoon,Han, Gi Uk,Lee, Kyungsup,Noh, Hee Chan,Lee, Phil Ho
, p. 3179 - 3187 (2021/09/02)
An efficient synthetic method for structurally various isochromenoindolones has been demonstrated through Rh(III)-catalyzed C?H activation followed by a cyclization reaction of N-methoxyarylamides with 3-diazooxindoles. The sequential reaction involves the streamlined formation of C?C and C?O bonds in one pot. The present method provides a broad range of isochromenoindolones as a new privileged scaffold in moderate to good yields with the release of methoxyamine and molecular nitrogen and has the benefits of a broad substrate scope and good functional group tolerance.
Reaction of 3-hydroxyquinoline-2,4-diones with isocyanates and thermally induced transformation of the reaction products
Mrkvicka, Vladimir,Lycka, Antonin,Vicha, Robert,Klasek, Antonin
experimental part, p. 78 - 91 (2011/03/16)
3-Hydroxyquinoline-2,4-diones 1 react with isocyanates to give novel 1,2,3,4-tetrahydro-2,4-dioxoquinolin-3-yl (alkyl/aryl)carbamates 2 and/or 1,9b-dihydro-9b-hydroxyoxazolo[5,4-c]quinoline-2,4(3aH,5H)-diones 3. Both of these compounds are converted, by boiling in cyclohexylbenzene solution in the presence of Ph3P or 4-(dimethylamino)pyridine, to give 3-(acyloxy)-1,3-dihydro-2H-indol-2-ones 8. All compounds were characterized by IR, and 1H- and 13C-NMR spectroscopy, as well as by EI mass spectrometry. Copyright
