6238-95-5

Basic information

• Product Name: benzyl 2-methyl-4-(4-nitrophenyl)-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxylate
• Synonyms: 3-pyridinecarboxylic acid, 1,4,5,6-tetrahydro-2-methyl-4-(4-nitrophenyl)-6-oxo-, phenylmethyl ester
• CAS NO: 6238-95-5
• Molecular Formula: C₂₀H₁₈N₂O₅
• Molecular Weight: 366.3673
• Mol File: 6238-95-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 596.5°C at 760 mmHg
• Flash Point: 314.5°C
• Density: 1.296g/cm³
• Vapor Pressure: 3.42E-14mmHg at 25°C
• Refractive Index: 1.604
• CAS DataBase Reference: benzyl 2-methyl-4-(4-nitrophenyl)-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl 2-methyl-4-(4-nitrophenyl)-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxylate(6238-95-5)
• EPA Substance Registry System: benzyl 2-methyl-4-(4-nitrophenyl)-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxylate(6238-95-5)

Safety Data

• Hazardous Substances Data: 6238-95-5(Hazardous Substances Data)

Upstream product

• 26518-76-3 6-(chloroacetyl)-2H-1,4-benzoxazin-3(4H)-one 
• 6322-56-1 4'-hydroxy-3'-nitroacetophenone 
• 26518-71-8 6-acetyl-4H-benzo[1,4]oxazin-3-one 
• 5466-88-6 3,4-dihydro-3-oxo-2H-1,4-benzoxazine 
• 94109-11-2 2-amino-4-ethylphenol 
• 6529-92-6 2-(2-chloro-acetylamino)-4-ethyl-phenol 

Downstream Products

• 6238-89-7 [2-(3,4-Dichloro-benzoylamino)-4-ethyl-phenoxy]-acetic acid 

Relevant articles and documents

Discovery of novel benzo[b][1,4]oxazin-3(4H)-ones as poly(ADP-ribose) polymerase inhibitors

Structure based drug design of a series of novel 1,4-benzoxazin-3-one derived PARP-1 inhibitors are described. The synthesis, enzymatic & cellular activities and pharmacodynamic effects are described. Optimized analogs demonstrated inhibition of poly-ADP-ribosylation in SW620 tumor bearing nude mice through 24 h following a single dose.

Anti-inflammatory properties of a series of phenyl- and phenoxy-alkanoic acids.

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