624-72-6

Basic information

• Product Name: 1,2-DIFLUOROETHANE
• Synonyms: 1,2-difluoro-ethan;CH2FCH2F;Ethane, 1,2-difluoro-;ethane,1,2-difluoro-;Ethylene difluolride;ethylenedifluoride;Fluorocarbon fc143;HFC152
• CAS NO: 624-72-6
• Molecular Formula: C₂H₄F₂
• Molecular Weight: 66.05
• EINECS: 200-866-1
• Product Categories: refrigerants
• Mol File: 624-72-6.mol
• Article Data: 9

Chemical Properties

• Melting Point: -118.59°C (estimate)
• Boiling Point: 31°C
• Appearance: /
• Density: 0,913 g/cm3
• Vapor Pressure: 1470mmHg at 25°C
• Refractive Index: 1.2800
• CAS DataBase Reference: 1,2-DIFLUOROETHANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-DIFLUOROETHANE(624-72-6)
• EPA Substance Registry System: 1,2-DIFLUOROETHANE(624-72-6)

Safety Data

• Hazard Codes: F,T
• Statements: 12
• Safety Statements: 3/7-9-16-33
• RIDADR: 3161
• HazardClass: GAS, TOXIC, FLAMMABLE
• Hazardous Substances Data: 624-72-6(Hazardous Substances Data)

Usage

General Description

1,2-Difluoroethane is a colorless, flammable gas with a faint, ethereal odor. It is used as a refrigerant and as a propellant in aerosol sprays. This chemical is also used as a blowing agent in the manufacture of foam plastics. 1,2-Difluoroethane is considered a volatile organic compound (VOC) and is regulated as an air pollutant in some jurisdictions. It is important to handle this chemical with care as it can be harmful if inhaled and may cause dizziness, drowsiness, and nausea. Exposure to high concentrations can cause asphyxiation and cardiac arrhythmias. Therefore, proper ventilation and personal protective equipment are necessary when working with 1,2-Difluoroethane.

InChI:InChI=1/C2H4F2/c3-1-2-4/h1-2H2

Upstream product

• 74-85-1 ethene 
• 504-63-2 trimethyleneglycol 
• 624-73-7 1,2-Diiodoethane 
• 79-38-9 Chlorotrifluoroethylene 
• 3744-29-4 fluoromethyl 
• 13709-36-9 xenon difluoride 
• 106-93-4 ethylene dibromide 
• 107-21-1 ethylene glycol 
• 82647-13-0 5-<3-(2-fluoroethyl)-1-triazenyl>-imidazole-4-carboxamide 
• 78604-18-9 1-(p-cyanophenyl)-3-(2-fluoroethyl)triazene 
• 453-14-5 1,3-difluoro-propan-2-one 
• 430-51-3 1-fluoro-2-propanone 

Downstream Products

• 75-02-5 1-fluoroethylene 
• 107-21-1 ethylene glycol 
• 431-06-1 1,2-difluoro-1,2-dichloroethene 
• 354-15-4 1,2,2-trichloro-1,2-difluoroethane 
• 76-12-0 CFC-112a 
• 338-64-7 1-Chloro-1,2-difluoroethane 
• 1842-05-3 1,1-dichloro-1,2-difluoroethane 
• 593-53-3 Methyl fluoride 
• 75-73-0 carbon tetrafluoride 
• 354-33-6 1,1,1,2,2-pentafluoroethane 
• 76-19-7 freon-218 
• 359-35-3 1,1,2,2-tetrafluoroethane 

Relevant articles and documents

Method for synthesizing 1,2-difluoroethane and 1,1,2-trifluoroethane

The invention relates to a method for synthesizing 1,2-difluoroethane and 1,1,2-trifluoroethane, belonging to the field of organic chemical synthesis. The method for synthesizing 1,2-difluoroethane and 1,1,2-trifluoroethane is characterized in that ethylene (with a molecular formula of CH2=CH2) and chlorine (with a molecular formula of Cl2) are heated under the action of a catalyst to generate a mixture of 1,2-dichloroethane and 1,1,2-trichloroethane, and the mixture and hydrogen fluoride (with a molecular formula HF) are heated under the action of a fluorination catalyst to generate 1,2-difluoroethane and 1,1,2-trifluoroethane. According to the method, raw materials are low in process and convenient to obtain; product separation and purification are simple; industrial production is easy;and industrial three-waste generation amount is low.

vic-difluorination of fluoroalkenes with xenon difiuoride: The effect of fluorine substituents on the reaction of alkenes with xenon difluoride

vic-Difluorination proceeds by the reaction of fluoroalkenes with xenon difluoride to afford the corresponding fluorinated compounds. From the reaction with polyfluoroalkenes, the products are obtained in high to excellent yields. In this reaction, the fluorine atom substituent of alkene stabilizes the cation intermediate and suppresses side-reactions such as rearrangement.

Reaction of diethylaminosulfur trifluoride with diols

Diethylaminosulfur trifluoride (DAST) reacts with dialcohols to give difluorides, sulfite esters or cyclic ethers depending on the number of carbons separating the two alcohol groups.Vicinal and 1,3-diols give large amounts of sulfite ester products while butane-1,4-diol gives almost exclusively the cyclic ether tetrahydrofuran.Terminal dialcohols longer than four carbons give primarily difluoride products.Semiempirical calculations indicate a preference for cyclic intermediates when four or less carbons separate the two alcohol moieties.These cyclic intermediates lead directly to the cyclic ethers and sulfite ester products.