6245-57-4

Usage

Uses

Used in Chemical Synthesis:
4-Methoxy-2-methylbenzoic acid is used as a key intermediate in the synthesis of various organic compounds, including 4-methoxy-2-methylbenzoates of Y(III) and lanthanides (III) (La to Lu, excluding Pm). These metal complexes have potential applications in various fields, such as catalysis, materials science, and as contrast agents in medical imaging.
Additionally, 4-Methoxy-2-methylbenzoic acid is used in the synthesis of 4-methoxy-2-methylbenzoic acid hydrazide and 5-bromo-4-methoxy-2-methylbenzoic acid. These derivatives can be further utilized in the development of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
4-Methoxy-2-methylbenzoic acid and its derivatives may have potential applications in the pharmaceutical industry as active pharmaceutical ingredients (APIs) or as intermediates in the synthesis of APIs. 4-Methoxy-2-methylbenzoic acid's unique structure and functional groups can be exploited to design and develop new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical industry, 4-Methoxy-2-methylbenzoic acid and its derivatives can be used as active ingredients in the development of new pesticides, herbicides, or insecticides. 4-Methoxy-2-methylbenzoic acid's chemical properties can be tailored to target specific pests or weeds, providing effective and environmentally friendly solutions for agriculture.
Used in Materials Science:
4-Methoxy-2-methylbenzoic acid and its metal complexes can be employed in materials science for the development of new materials with unique properties. These materials can be used in various applications, such as sensors, catalysts, or advanced materials for energy storage and conversion.

InChI:InChI=1/C9H10O3/c1-6-5-7(12-2)3-4-8(6)9(10)11/h3-5H,1-2H3,(H,10,11)

Upstream product

• 52289-54-0 4-methoxysalicylaldehyde 
• 52289-55-1 (4-methoxy-2-methylphenyl)methanol 
• 63452-69-7 1-iodo-4-methoxy-2-methylbenzene 
• 24826-74-2 1-(4-methoxy-2-methylphenyl)ethanone 
• 104178-07-6 5-Methoxy-2-dimethylaminomethyl-toluol 
• 4685-47-6 3,4-dimethylanisole 
• 100-09-4 4-methoxybenzoic acid 
• 74-88-4 methyl iodide 
• 103562-90-9 1-(4-methoxy-2-methylbenzoyl)-4-methylpiperazine 
• 110175-18-3 3-methyl-4-(trinitromethyl)anisole 
• 7697-37-2 nitric acid 
• 7782-50-5 chlorine 
• 53773-74-3 3-methyl-4-propenyl-anisole 
• 22572-29-8 4-methoxy-2-methyl-1-vinylbenzene 

Downstream Products

• 1885-13-8 4-methoxyphthalic acid 
• 35598-05-1 methyl 4-methoxy-2-methylbenzoate 
• 95420-39-6 2-(4-Methoxy-2-methyl-phenyl)-3H-imidazo[4,5-c]pyridine; hydrochloride 
• 31310-08-4 2-methyl-4-methoxybenzoyl chloride 
• 578-39-2 4-hydroxy-2-methylbenzoic acid 
• 52289-55-1 (4-methoxy-2-methylphenyl)methanol 
• 857641-37-3 4-nitrophenyl 4-methoxy-2-methylbenzoate 
• 29336-53-6 4-hydroxy-2-methylphenylacetic acid 
• 942-97-2 4-methoxy-2-methylphenylacetic acid 
• 127817-93-0 N-(4-Hydroxyphenyl)-N-(1,1,1-trifluor-2-propyl)-4-hydroxy-2-methylbenzamid 
• 127817-87-2 N-(4-Methoxyphenyl)-N-(1,1,1-trifluor-2-propyl)-4-methoxy-2-methylbenzamid 
• 103562-90-9 1-(4-methoxy-2-methylbenzoyl)-4-methylpiperazine 
• 864178-60-9 tert-butyl 2-(4-methoxy-3-methylbenzoyl)hydrazinecarboxylate 
• 68294-03-1 2-(carboxymethyl)-4-methoxybenzoic acid 

Relevant academic research and scientific papers

Cyhalofop-containing pesticide composition and application thereof

The invention discloses a pesticide composition containing cyhalofop-butyl and application thereof, belongs to the technical field of pesticide preparation and comprises 10 - 20 parts of cyhalofop-butyl. Tetramethyl chloride 3-5 parts, synergistic microcapsule 8-13 parts, wetting agent 1.5 - 4.5 parts, dispersing agent 1-3 parts, defoaming agent 0.5 - 1.5 parts and water 40 - 50 parts. When the water in the soil is less, the weed is absorbed by the chitosan so as to accelerate the absorption of A the synergic microcapsule and the cyhalofop-butyl ester, so that the pesticide composition is greatly reduced per mu.

6-chloro-5-hydroxyisoindole-1-one and synthesis method thereof

The invention belongs to the technical field of organic synthesis, and relates to 6-chloro-5-hydroxyisoindole-1-one and a synthesis method thereof. The preparation method of the compound comprises thefollowing steps: taking 1-bromo-4-methoxy-2-methyl benz

Chemical synthesis method of 6-bromo-5-hydroxyl iso-indolin-1-ketone

The invention belongs to the field of chemical synthesis, and particularly relates to 6-bromo-5-hydroxyl iso-indolin-1-ketone as well as a chemical synthesis method thereof. A synthetic route of the method is as follows: (shown in the description). The ch

Site- and regio-selective incorporation of carbon dioxide into the C(sp2)Si bond of benzosilacyclobutenes

A reaction of benzosilacyclobutenes with carbon dioxide is catalyzed by a nickel complex having an N-heterocyclic carbene ligand. Carbon dioxide inserts into the C(sp2)Si bond in a site- and regio-selective manner to form a carboncarbon bond, furnishing benzoic acid derivatives.

Metal-free oxidative cleavage of the C-C bond in α-hydroxy-β-oxophosphonates

The potential of TBHP to promote oxidative hydroxylation of α-hydroxy-β-oxophosphonates (HOPs) through C(CO)-C bond cleavage is described. This cleavage, as depicted in the mechanism is expected through an isomer of HOP that reacts with TBHP to generate acids.

DMSO/I2 mediated C-C bond cleavage of α-ketoaldehydes followed by C-O bond formation: A metal-free approach for one-pot esterification

A novel and efficient I2/DMSO mediated metal-free strategy is presented for the direct C-C bond cleavage of aryl-/heteroaryl- or aliphatic α-ketoaldehydes by C2-decarbonylation and C1-carbonyl oxidation to give the corresponding carboxylic acids followed by esterification in one pot, offering excellent yields in both the steps. Here, DMSO acts as the oxygen source/oxidant and this reaction works very well under both conventional heating and microwave irradiation. This is a very simple and convenient protocol.

An outstanding catalyst for the oxygen-mediated oxidation of arylcarbinols, arylmethylene and arylacetylene compounds

A convenient and sustainable protocol for the aerobic oxidation of benzyl alcohols to carbonyl compounds, based on the use of 1,2,4-triazole-type ligands and nickel(ii) bromide, is described. This combination leads to the formation of an exceedingly active, enzyme-like system that allows for other oxidative processes, such as benzylic C-H oxidation and oxygen-mediated cleavage of C-C triple bond, a pioneering procedure for transformation of alkynes into carboxylic acids.

A Metal-Free Approach to Carboxylic Acids by Oxidation of Alkyl, Aryl, or Heteroaryl Alkyl Ketones or Arylalkynes

The metal-free oxidation of dialkyl, alkyl aryl, or alkyl heteroaryl ketones or arylalkynes to the corresponding carboxylic acids is achieved using an oxidative mixture of Oxone and trifluoroacetic acid. This green method is a simple and mild protocol to obtain carboxylic derivatives in excellent yields.

Series of structural and functional models for the ES (enzyme-substrate) complex of the Co(II)-containing quercetin 2,3-dioxygenase

A series of mononuclear CoII-flavonolate complexes [Co IILR(fla)] (LRH = 2-{[bis(pyridin-2-ylmethyl) amino]methyl}-p/m-R-benzoic acid; R = p-OMe (1), p-Me (2), m-Br (4), and m-NO2 (5); fla = flavonolate) were designed and synthesized as structural and functional models for the ES (enzyme-substrate) complexes to mimic the active site of the Co(II)-containing quercetin 2,3-dioxygenase (Co-2,3-QD). The metal center Co(II) ion in each complex shows a similar distorted octahedral geometry. The model complexes display high enzyme-type dioxygenation reactivity (oxidative O-heterocyclic ring opening of the coordinated substrate flavonolate) at low temperature, presumably due to the attached carboxylate group in the ligands. The reactivity exhibits a substituent group dependent order of -OMe (1) > -Me (2) > -H (3)14b > -Br (4) > -NO2 (5), and the Hammett plot is linear (ρ = -0.78). This can be explained as the electronic nature of the substituent group in the ligands may influence the conformation and redox potential of the bound flavonolate and finally bring different reactivity. The structures, properties, and reactivity of the model complexes show some dependence on the substituent group in the supporting model ligands, and there is some relationship among them. This study is the first example of a series of structural and functional ES models of Co-2,3-QD, with focus on the effects of the electronic nature of substituted groups and the carboxylate group of the ligands to the dioxygenation reactivity, that will provide important insights into the structure-property-reactivity relationship and the catalytic role of Co-2,3-QD.

The Continuous-Flow Synthesis of Carboxylic Acids using CO2 in a Tube-In-Tube Gas Permeable Membrane Reactor

Keep it simple: A gas-liquid flow reactor has been developed based on a gas permeable tube-in-tube configuration which effectively delivers gas to a liquid substrate stream in a safe, continuous fashion. A series of carboxylic acids were prepared from the reaction of CO2 with a range of Grignard reagents (see picture).