62455-56-5

Usage

Uses

Used in Organic Synthesis:
2-(4-CHLOROBENZOYL)-3,3-DI(METHYLTHIO)ACRYLONITRILE is used as a key intermediate in the synthesis of specialty chemicals due to its reactive acrylonitrile group and the presence of a chloro substituent, which can be further functionalized in various chemical reactions.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-(4-CHLOROBENZOYL)-3,3-DI(METHYLTHIO)ACRYLONITRILE is used as a building block for the development of new drugs, leveraging its unique structural features to create molecules with potential biological activities and medicinal properties.
Used in Polymer Production:
2-(4-CHLOROBENZOYL)-3,3-DI(METHYLTHIO)ACRYLONITRILE is used as a monomer in the production of polymers, where its specific chemical and physical properties can contribute to the development of materials with tailored characteristics for various applications.
Used in Agrochemicals:
In the agrochemical sector, 2-(4-CHLOROBENZOYL)-3,3-DI(METHYLTHIO)ACRYLONITRILE is used as a precursor for the synthesis of agrochemicals, such as pesticides and herbicides, due to its potential to form active ingredients with desired biological properties.

InChI:InChI=1/C12H10ClNOS2/c1-16-12(17-2)10(7-14)11(15)8-3-5-9(13)6-4-8/h3-6H,1-2H3

Upstream product

• 75-15-0 carbon disulfide 
• 4640-66-8 p-chlorobenzoylacetonitrile 
• 74-88-4 methyl iodide 
• 41467-26-9 1-(4-chlorophenyl)-3,3-bis(methylsulfanyl)-2-propen-1-one 
• 544-92-3 copper(I) cyanide 
• 98606-78-1 2-bromo-1-(4-chlorophenyl)-3,3-bis(methylthio)prop-2-en-1-one 

Downstream Products

• 68364-89-6 5-(4-chloro-phenyl)-3-methylsulfanyl-isoxazole-4-carbonitrile 
• 118603-68-2 1-(4-Chlorobenzoyl)-1-cyano-2-methylthio-2-n-propylamino ethene 
• 63244-05-3 methyl 4-(4-chlorophenyl)-3-cyano-2-methylthio-5-thiophenecarboxylate 
• 96232-47-2 3-(4-Chloro-phenyl)-1-methyl-5-methylsulfanyl-1-oxo-1λ⁶-thiopyran-4-carbonitrile 

Relevant academic research and scientific papers

ALKYLIERUNGS- AND ARYLIERUNGSREAKTIONEN MIT GEMINALEN DITHIOLATEN

Acyl acetonitriles 1 react with carbon disulfide in the presence of sodium hydride to give disodium salts 2.Treatment of 2 with an alkylation reagent yields the open chain or cyclic acyl cyanketene S,S-acetals 3,4,8 and 10, respectively.Arylation to 11 is successful with 2,4-dinitro-chlorobenzene.Adding only one equivalent of methyl iodide to 2 and acidifying the reaction mixture lead to the monoalkylated compounds 7, whereas β-hydroxythioanilides 12 are available by reaction of 1 with phenyl isothiocyanate.A comparison of the ?-values shows that there exists the same type of the proton's chelation of the OH-group in 7 and 12.