626-46-0 Usage
Uses
Used in Dye Manufacturing:
Phenol, 3,5-diaminois used as a key intermediate in the production of various dyes, contributing to the coloration and stability of the final products.
Used in Fiber Production:
Phenol, 3,5-diaminois used as a chemical component in the synthesis of fibers, enhancing their properties and performance in various applications.
Used in Resin Production:
Phenol, 3,5-diaminois used as a raw material in the formulation of resins, which are essential in the production of plastics and coatings.
Used in Rubber Industry:
Phenol, 3,5-diaminois used as an antioxidant and antiozonant in the rubber industry, improving the durability and resistance of rubber products to environmental factors.
Used in Pharmaceutical Industry:
Phenol, 3,5-diaminois used as a starting material for the synthesis of various pharmaceutical compounds, including drugs and medications.
Used in Chemical Research:
Phenol, 3,5-diaminois used as a reagent in various chemical reactions and processes, contributing to the advancement of scientific knowledge and the development of new chemical products.
Check Digit Verification of cas no
The CAS Registry Mumber 626-46-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,2 and 6 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 626-46:
(5*6)+(4*2)+(3*6)+(2*4)+(1*6)=70
70 % 10 = 0
So 626-46-0 is a valid CAS Registry Number.
626-46-0Relevant academic research and scientific papers
Scope and Optimization of the Double Knorr Cyclization: Synthesis of Novel Symmetrical and Unsymmetrical Tricyclic 1,8-Diazaanthraquinones
Prior, Allan M.,Sun, Dianqing
supporting information, p. 859 - 871 (2018/02/10)
The Knorr cyclization of β-ketoanilides to form 2-quinolones in the presence of acid is well documented chemistry. Double Knorr cyclization is rare, with very few examples appearing in the literature to date. The double Knorr methodology can provide access to tricyclic 1,8-diazaanthraquinones, a scaffold seen in the diazaquinomycin family. The optimized synthesis of diazaquinomycin A and structural analogues thereof via double Knorr cyclization of di-β-ketoanilide precursor substrates is reported. The scope and generality of the double Knorr cyclization were investigated along with an optimization study. The double Knorr cyclization was found to be sensitive to steric bulk on precursor substrates. In addition, the presence of a 5-hydroxy group on the 1,3-di-β-ketoanilide facilitated the double Knorr cyclization, possibly due to its stabilizing effect on the carbocation intermediates formed during the reaction.
