6265-93-6

Usage

Uses

Used in Pharmaceutical Industry:
(6E)-6-(1,3-benzothiazol-2(3H)-ylidene)-2-methoxycyclohexa-2,4-dien-1-one is used as an intermediate in the synthesis of pharmaceutical compounds due to its potential biological activities. Its unique structure allows for the development of new drugs with specific therapeutic properties.
Used in Chemical Research:
In the field of chemical research, (6E)-6-(1,3-benzothiazol-2(3H)-ylidene)-2-methoxycyclohexa-2,4-dien-1-one serves as a valuable compound for studying the properties and reactions of heterocyclic compounds. Its structure can provide insights into the behavior of similar compounds and contribute to the advancement of organic chemistry.
Used in Material Science:
(6E)-6-(1,3-benzothiazol-2(3H)-ylidene)-2-methoxycyclohexa-2,4-dien-1-one may also find applications in material science, particularly in the development of new materials with specific properties. Its unique structure could be exploited to create materials with enhanced characteristics, such as improved stability or reactivity.

Upstream product

• 98370-54-8 zinc 2-aminobenzenethiolate 
• 148-53-8 3-methoxy-2-hydroxybenzaldehyde 
• 877-22-5 3-methoxysalicylic acid 
• 137-07-5 2-amino-benzenethiol 
• 52-90-4 L-Cysteine 
• 1362772-43-7 C₁₇H₁₃NO₃S 
• 454-28-4 D-homocysteine 
• 60-23-1 Cysteamine 
• 1403894-38-1 C₂₆H₁₈N₂O₃S₃ 
• 1478061-68-5 C₃₄H₂₈N₂O₆S₄ 

Downstream Products

• 1362772-43-7 C₁₇H₁₃NO₃S 
• 1403894-38-1 C₂₆H₁₈N₂O₃S₃ 
• 90481-43-9 2-(2,3-dihydroxyphenyl)-1,3-benzothiazole 

Relevant academic research and scientific papers

Exploring the hidden potential of a methoxy substituted HBT derivative as an efficient example of coupling of AIE and ESIPT processes and as an energy harvesting platform

A methoxy substituted HBT derivative, namely 2-(benzo[d]thiazol-2-yl)-6-methoxyphenol (TMP), was synthesized and characterized. Detailed photophysical investigation of TMP indicated the coupling of excited state intramolecular proton transfer (ESIPT) and

A boronate-based ratiometric fluorescent probe for fast selective detection of peroxynitrite

Given that peroxynitrite (ONOO?) is profoundly associated with health and diseases, a new fluorescent probe ABT was designed and synthesized for detection of ONOO?. ABT manifested not only ratiometric fluorescence signals simultaneou

Product-boosted fluorescence signal: A new approach for designing small-molecule probes for detection of peroxynitrite

In situ self-assembled boronate ester comprising commercially available 2-formylphenylboronic acid and 2-(2′,3′-bihydroxyphenyl)benzothiazole (BHBT) is explored for the detection of ONOO- with product-boosted fluorescence. The self-assembly can detect ONO

Selective and sensitive detection and quantification of human carboxylesterase 1 by a ratiometric fluorescence probe

A novel ratiometric fluorescent probe derived from 2-(2′-hydroxy-3′-methoxyphenyl) benzothiazole (HMBT) for human carboxylesterase 1 (hCES1) has been synthesized and well characterized. The probe was designed by modulating the excited state intramolecular

Kinetic study of the complex reaction between copper(II) and 2-(2′-hydroxy-3′-methoxyphenyl)benzothiazole

2-(2′-Hydroxy-3′-methoxyphenyl)benzothiazole reacts with copper(II) in an ethanol/water mixture to form an O,S chelate which exhibits the remarkable property of changing the chelation site above a pH of ca. 5.0, to the O,N site. The detailed kinetics of t

Cascade reaction-based fluorescent probe for detection of H2S with the assistance of CTAB micelles

We report a turn-on fluorescent probe for H2S through a cascade reaction using a new trap group 4-(bromomethyl)benzoate, based on excited-state intramolecular proton transfer (ESIPT) sensing mechanism. The probe showed good selectivity and high

A turn-on fluorescent sensor for selective detection of hydrazine and its application in Arabidopsis thaliana

In this work, a primary method was constructed for detecting hydrazine in plant, thus accomplished the closed-loop monitoring of hydrazine circulation within manufacture, environment, plants, animals and human. From a series of sensors, QYL-1 was selected

A chloroacetate based ratiometric fluorescent probe for cysteine detection in biosystems

The specific detection of cysteine (Cys) over homocysteine (Hcy), glutathione (GSH) and other amino acids is of great significance for studying its biological functions as well as for the diagnosis of related diseases. Chloroacetyl group was often used as a reaction site for cysteine fluorescent probes for its sensitivity and selectivity. However, high background fluorescence and low stability are common problems encountered by such probes. Here, four chloroacetyl group based fluorescent probes (C1, C2, C3, and H4) was synthesized for a comparative study. We found that the inefficient quenching ability of chloroacetyl group turned into an advantage when connected with a ratiometric fluorophore. With the modification of chloroacetyl group, probe H4 displayed excellent ratiometric property and great selectivity for Cys, the stability was also improved. Additionally, the probe was successfully applied for quantitative detection of Cys in fetal bovine serum and real-time imaging in living HeLa cells with low toxicity.

ESIPT-based fluorescence probe for the ratiometric detection of superoxide

A simple ESIPT-based fluorescence probe (HMBT-LW) was developed for the detection of superoxide (O2?). HMBT-LW was synthesised over two steps and was shown to rapidly detect low concentrations of O2? (limit of detection =

The invention relates to a thiazole as a matrix of the acrylic ester compound as the fluorescent probe application and its preparation method (by machine translation)

The invention relates to a thiazole as a matrix of the acrylic ester compound as the fluorescent probe application and its preparation method, the preparation of the fluorescent probe BTHA in dimethyl sulfoxide and 4 - hydroxyethyl piperazine ethyl sulfon